Resultados NCBI + Uniprot

Depois de termos tanto os resultados do NCBI para cada uma das proteínas, bem como os da Uniprot, resolvemos compilar os resultados obtidos em ambas as bases de dados numa única tabela e comparar os mesmos. Os resultados da Uniprot permitiram complementar a informação obtida no NCBI, uma vez que, para algumas proteínas, dados como a função das mesmas estão especificadas com um maior nível de detalhe. Além disso, detetamos diferenças em 22 dos resultados entre as bases de dados, os quais estão sublinhados a azul. Optamos por considerar os resultados da Uniprot mais corretos, uma vez que as entradas se encontram revistas nesses casos.

Com os resultados do NCBI e da Uniprot, mais concretamente das funções e das classes dos processos biológicos, construimos um gráfico de cores que agrupa os genes/proteínas consoante a classe biológica funcional a que pertence. Algumas proteínas têm associadas mais do que uma função, contudo, optamos por colorir o retângulo que a representa com a função que consideramos mais importante.

Figura 1 - Classificação funcional das genes/proteínas e respetiva legenda.

import os, sys, inspect, math
import pandas as pd
from IPython.core.display import display, HTML

def import_modules():
    """
    Importar os módulos que desenvolvemos neste trabalho.
    """
    current_dir = os.path.dirname(os.path.abspath(inspect.getfile(inspect.currentframe())))
    parent_dir = os.path.dirname(current_dir)
    sys.path.insert(0, parent_dir)

def itemize(l):
    """
    Criar uma lista HTML.
    """
    if isinstance(l, float) and math.isnan(l):
        return ""
    if isinstance(l, dict):
        return itemize_dict(l)

    html = "<ul>"
    for i in l:
        html += "<li>"
        if isinstance(i, dict):
            html += itemize_dict(i)
        else:
            html += i
        html +="</li>"
    html += "</ul>"
    return html

def itemize_dict(d):
    """
    Criar uma lista HTML dado um dicionário.
    """
    html = "<ul>"
    for k in d:
        html += "<li><strong>" + k + ":</strong> " + str(d[k]) + "</li>"  
    html += "</ul>"
    return html

def pretty_print(v):
    """
    Remove valores NaN e None.
    """
    if isinstance(v, float) and math.isnan(v):
        return ""
    if v is None:
        return ""
    return v

def background_it(v):
    """
    Torna o background azul.
    """
    return "<div style=\"background-color:powderblue;\">" + str(v) + "</div>"

def shorten_it(v):
    """
    Retorna uma string mais pequena + "..."
    """
    return v[:10] + "..."

def main():
    import_modules()
    import util.rw as rw
    
    # mostra todas as linhas
    pd.options.display.max_rows = 250
    
    # não truncar informação
    pd.set_option('display.max_colwidth', -1)

    cdd = rw.read_json("files/domains.json")
    ncbi = rw.read_json("files/.ncbi_uniprot.json")
    diff = rw.read_json("files/.ncbi_uniprot_diff.json")

    columns_to_itemize = [
        "location",
        "accessions",
        "cofactors",
        "comment_functions",
        "molecular_functions",
        "biological_processes",
        "domains",
        "locations",
        "pdbs",
        "modified_residues"
    ]
        
    columns_to_pp = [
        "gene",
        "EC_number",
        "uniprot_id",
        "protein_id",
        "organism",
        "length",
        "mass",
        "translation"
    ]

    columns_to_show = [
        "short_name",
        "product",
        "gene",
        "EC_number",
        "accessions",
        "status",
        "type",
        "uniprot_id",
        "protein_id",
        "organism",
        "location",
        "length",
        "mass",
        "comment_functions",
        "molecular_functions",
        "biological_processes",
        "domains",
        "locations",
        "cofactors",
        "pdbs",
        "modified_residues",
        "translation"
    ]
    
    df = pd.DataFrame(ncbi).transpose()
    
    # adicionar os dominios
    l = []
    for tag in sorted(ncbi.keys()):
        if tag in cdd:
            domains = cdd[tag]["domains"]
        else:
            domains = []
        l.append(domains)

    df["domains"] = l
        
    for p in columns_to_itemize:
        df[p] = df[p].apply(itemize)
        
    for p in columns_to_pp:
        df[p] = df[p].apply(pretty_print)
        
    # mostrar parte da translação
    df["translation"] = df["translation"].apply(shorten_it)
    
    # marcar a informação que difere nos sites NCBI e UniProt
    for tag in diff:
        for p in diff[tag]:
            df[p][tag] = background_it(df[p][tag])

    display(HTML(df[columns_to_show].to_html(escape=False)))

    
main()

	short_name	product	gene	EC_number	accessions	status	type	uniprot_id	protein_id	organism	location	length	mass	comment_functions	molecular_functions	biological_processes	domains	locations	cofactors	pdbs	modified_residues	translation
lpg0232	Q5ZYX9_LEGPH	Transcriptional regulator np20, Fur family	np20		Q5ZYX9	unreviewed	mRNA	Q5ZYX9	YP_094286.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 270569 strand: 1 start: 270036	177	20453		DNA binding transcription factor activity, sequence-specific DNA binding		accession: COG0735 name: Fur desc: Fe2+ or Zn2+ uptake regulation protein [Inorganic ion transport and metabolism]					MIGCCLIIFP...
lpg0233	Q5ZYX8_LEGPH	Benzoylformate decarboxylase	mdlC	4.1.1.7	Q5ZYX8	unreviewed	mRNA	Q5ZYX8	YP_094287.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 272278 strand: -1 start: 270686	530	58497		benzoylformate decarboxylase activity magnesium ion binding thiamine pyrophosphate binding		accession: cd02002 name: TPP_BFDC desc: Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module accession: pfam02776 name: TPP_enzyme_N desc: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain accession: pfam00205 name: TPP_enzyme_M desc: Thiamine pyrophosphate enzyme, central domain accession: COG0028 name: IlvB desc: Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme					MKKTGSDVLK...
lpg0234	Q5ZYX7_LEGPH	SidE	sidE		Q5ZYX7	unreviewed	mRNA	Q5ZYX7	YP_094288.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 277121 strand: -1 start: 272577	1514	171651				accession: pfam12252 name: SidE desc: Dot/Icm substrate protein This family of proteins is found in bacteria					MLIFKSQILI...
lpg0235	Q5ZYX6_LEGPH	Uncharacterized protein			Q5ZYX6	unreviewed	mRNA	Q5ZYX6	YP_094289.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 277987 strand: -1 start: 277484	167	19095		carbon-sulfur lyase activity	metabolic process	accession: cl01553 name: GFA super family desc: Glutathione-dependent formaldehyde-activating enzyme					MKKAFRIMAT...
lpg0236	Q5ZYX5_LEGPH	Uncharacterized protein			Q5ZYX5	unreviewed	mRNA	Q5ZYX5	YP_094290.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 280039 strand: -1 start: 278060	659	77097									MRYTNIELLK...
lpg0237	Q5ZYX4_LEGPH	Lipolytic enzyme	mhpC		Q5ZYX4	unreviewed	mRNA	Q5ZYX4	YP_094291.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 281114 strand: 1 start: 280320	264	29403				accession: pfam12695 name: Abhydrolase_5 desc: Alpha/beta hydrolase family accession: cl21494 name: Abhydrolase super family desc: alpha/beta hydrolases					MATLKINGVD...
lpg0238	Q5ZYX3_LEGPH	Glycine betaine aldehyde dehydrogenase	gbsA	1.2.1.8	Q5ZYX3	unreviewed	mRNA	Q5ZYX3	YP_094292.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 282597 strand: 1 start: 281131	488	52945		betaine-aldehyde dehydrogenase activity		accession: cd07119 name: ALDH_BADH-GbsA desc: Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like					MEIYKMYIDG...
lpg0239	Q5ZYX2_LEGPH	4-aminobutyrate aminotransferase	gabT	2.6.1.19	Q5ZYX2	unreviewed	mRNA	Q5ZYX2	YP_094293.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 283924 strand: 1 start: 282572	450	49049		4-aminobutyrate transaminase activity pyridoxal phosphate binding	gamma-aminobutyric acid metabolic process	accession: cl18945 name: AAT_I super family desc: Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes accession: COG0160 name: GabT desc: 4-aminobutyrate aminotransferase or related aminotransferase					MKHQLVGTKL...
lpg0240	Q5ZYX1_LEGPH	DNA repair protein	recN		Q5ZYX1	unreviewed	mRNA	Q5ZYX1	YP_094294.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 284787 strand: 1 start: 284008	259	29552									MNDIMWYQNI...
lpg0241	GLSA_LEGPH	Glutaminase		3.5.1.2	Q5ZYX0	reviewed	mRNA	Q5ZYX0	YP_094295.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 285979 strand: 1 start: 285047	310	33970		glutaminase activity	glutamine metabolic process	accession: TIGR03814 name: Gln_ase desc: glutaminase A					MSSKLLTIQL...
lpg0242	Q5ZYW9_LEGPH	D-3-phosphoglycerate dehydrogenase	serA	1.1.1.95	Q5ZYW9	unreviewed	mRNA	Q5ZYW9	YP_094296.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 286990 strand: 1 start: 286103	295	32454		NAD binding phosphoglycerate dehydrogenase activity		accession: cl21454 name: NADB_Rossmann super family desc: Rossmann-fold NAD(P)(+)-binding proteins accession: COG0111 name: SerA desc: Phosphoglycerate dehydrogenase or related dehydrogenase					MKIAVVEPIG...
lpg0243	Q5ZYW8_LEGPH	Short chain dehydrogenase			Q5ZYW8	unreviewed	mRNA	Q5ZYW8	YP_094297.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 287802 strand: -1 start: 287203	199	21183				accession: PRK07578 name: PRK07578 desc: short chain dehydrogenase Provisional					MKIVVIGATG...
lpg0244	Q5ZYW7_LEGPH	Pyridine nucleotide-disulfide oxidoreductase		1.16.1.1	Q5ZYW7	unreviewed	mRNA	Q5ZYW7	YP_094298.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 289402 strand: -1 start: 288008	464	50768		flavin adenine dinucleotide binding mercury (II) reductase activity	cell redox homeostasis	accession: pfam02852 name: Pyr_redox_dim desc: Pyridine nucleotide-disulphide oxidoreductase, dimerization domain accession: pfam00070 name: Pyr_redox desc: Pyridine nucleotide-disulphide oxidoreductase accession: PRK06370 name: PRK06370 desc: mercuric reductase	cell				MVLEFDTIIL...
lpg0245	Q5ZYW6_LEGPH	NAD-glutamate dehydrogenase			Q5ZYW6	unreviewed	mRNA	Q5ZYW6	YP_094299.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 292834 strand: -1 start: 289454	1126	128304		glutamate dehydrogenase (NAD+) activity	glutamate catabolic process to 2-oxoglutarate	accession: pfam05088 name: Bac_GDH desc: Bacterial NAD-glutamate dehydrogenase accession: COG2902 name: Gdh2 desc: NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]					MHGILRMMTN...
lpg0246	Q5ZYW5_LEGPH	Uncharacterized protein			Q5ZYW5	unreviewed	mRNA	Q5ZYW5	YP_094300.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 293739 strand: 1 start: 293014	241	28266					integral component of membrane				MYKNILFFSN...
lpg0247	Q5ZYW4_LEGPH	Uncharacterized protein			Q5ZYW4	unreviewed	mRNA	Q5ZYW4	YP_094301.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 294924 strand: 1 start: 293971	317	36800									MRVFYGLLGF...
lpg0248	Q5ZYW3_LEGPH	Arsenate reductase		1.20.4.1	Q5ZYW3	unreviewed	mRNA	Q5ZYW3	YP_094302.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 295425 strand: 1 start: 295084	113	13051		arsenate reductase (glutaredoxin) activity		accession: cd03034 name: ArsC_ArsC desc: Arsenate Reductase (ArsC) family, ArsC subfamily					MEKITIYHNP...
lpg0249	Q5ZYW2_LEGPH	Stearoyl CoA 9-desaturase		1.14.19.1	Q5ZYW2	unreviewed	mRNA	Q5ZYW2	YP_094303.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 296666 strand: -1 start: 295512	384	45050		stearoyl-CoA 9-desaturase activity	lipid metabolic process	accession: cl00615 name: Membrane-FADS-like super family desc: The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane ... accession: cl24015 name: MULE super family desc: MULE transposase domain This domain was identified by Babu and colleagues. accession: pfam00487 name: FA_desaturase desc: Fatty acid desaturase	integral component of membrane				MMFGFLNMTL...
lpg0250	Q5ZYW1_LEGPH	ATP-dependent RNA helicase, DEAD box family			Q5ZYW1	unreviewed	mRNA	Q5ZYW1	YP_094304.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 298029 strand: -1 start: 296785	414	45988		ATP binding helicase activity nucleic acid binding		accession: cd00268 name: DEADc desc: DEAD-box helicases. accession: cd00079 name: HELICc desc: Helicase superfamily c-terminal domain					MSFKQLALIE...
lpg0251	Q5ZYW0_LEGPH	RNA binding protein, cold-inducible rrm			Q5ZYW0	unreviewed	mRNA	Q5ZYW0	YP_094305.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 298636 strand: 1 start: 298358	92	10481		nucleic acid binding nucleotide binding		accession: cl17169 name: RRM_SF super family desc: RNA recognition motif (RRM) superfamily accession: COG0724 name: RRM desc: RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]					MMKQKKIYVG...
lpg0252	Q5ZYV9_LEGPH	Membrane protein			Q5ZYV9	unreviewed	mRNA	Q5ZYV9	YP_094306.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 299489 strand: 1 start: 298794	231	25867				accession: PRK11212 name: PRK11212 desc: hypothetical protein Provisional	integral component of membrane				MVIIVSMKAN...
lpg0253	Q5ZYV8_LEGPH	Acetyltransferase, GNAT family			Q5ZYV8	unreviewed	mRNA	Q5ZYV8	YP_094307.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 300165 strand: 1 start: 299524	213	24743		N-acetyltransferase activity		accession: pfam00583 name: Acetyltransf_1 desc: Acetyltransferase (GNAT) family accession: COG1670 name: RimL desc: Protein N-acetyltransferase, RimJ/RimL family					MMLTGLRLLT...
lpg0254	Q5ZYV7_LEGPH	Uncharacterized protein			Q5ZYV7	unreviewed	mRNA	Q5ZYV7	YP_094308.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 300827 strand: 1 start: 300258	189	22043									MSEYLVLPAR...
lpg0255	Q5ZYV6_LEGPH	Outer membrane channel protein			Q5ZYV6	unreviewed	mRNA	Q5ZYV6	YP_094309.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 302328 strand: 1 start: 300982	448	50351		lipid binding transporter activity		accession: pfam02321 name: OEP desc: Outer membrane efflux protein accession: pfam02321 name: OEP desc: Outer membrane efflux protein	cell outer membrane integral component of membrane				MYRKRWLILL...
lpg0256	Q5ZYV5_LEGPH	Conserved domain protein			Q5ZYV5	unreviewed	mRNA	Q5ZYV5	YP_094310.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 303355 strand: 1 start: 302309	348	40049			transport	accession: pfam13515 name: FUSC_2 desc: Fusaric acid resistance protein-like	integral component of membrane plasma membrane				MVPVGIDQQK...
lpg0257	Q5ZYV4_LEGPH	Multidrug resistance secretion protein			Q5ZYV4	unreviewed	mRNA	Q5ZYV4	YP_094311.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 304404 strand: 1 start: 303412	330	37929				accession: pfam13533 name: Biotin_lipoyl_2 desc: Biotin-lipoyl like accession: pfam13437 name: HlyD_3 desc: HlyD family secretion protein accession: COG1566 name: EmrA desc: Multidrug resistance efflux pump [Defense mechanisms]	integral component of membrane				MSDKPKAGFP...
lpg0258	Q5ZYV3_LEGPH	Uncharacterized protein			Q5ZYV3	unreviewed	mRNA	Q5ZYV3	YP_094312.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 306524 strand: 1 start: 304581	647	70909					integral component of membrane				MKIPFEGKWR...
lpg0259	Q5ZYV2_LEGPH	Uncharacterized protein			Q5ZYV2	unreviewed	mRNA	Q5ZYV2	YP_094313.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 308327 strand: 1 start: 306543	594	65768									MKREFFQKLD...
lpg0260	Q5ZYV1_LEGPH	Uncharacterized protein			Q5ZYV1	unreviewed	mRNA	Q5ZYV1	YP_094314.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 308911 strand: 1 start: 308513	132	14657									MFGFFSDYKQ...
lpg0261	Q5ZYV0_LEGPH	ISSod6 transposase, ISI301			Q5ZYV0	unreviewed	mRNA	Q5ZYV0	YP_094315.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 309605 strand: -1 start: 309426	59	7041				accession: cl21562 name: DDE_Tnp_4 super family desc: DDE superfamily endonuclease accession: COG3293 name: COG3293 desc: Transposase [Mobilome: prophages, transposons]					MVNLKSVLRI...
lpg0262	Q5ZYU9_LEGPH	Bacteriophage related DNA polymerase		2.7.7.7	Q5ZYU9	unreviewed	mRNA	Q5ZYU9	YP_094316.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 310310 strand: -1 start: 309672	212	24258		DNA-directed DNA polymerase activity		accession: cd10030 name: UDG_F4_TTUDGA_like desc: Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms					MSDVLNNYYL...
lpg0263	Q5ZYU8_LEGPH	MFS transporter family protein			Q5ZYU8	unreviewed	mRNA	Q5ZYU8	YP_094317.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 311841 strand: 1 start: 310567	424	46700				accession: cd06174 name: MFS desc: Major Facilitator Superfamily (MFS) accession: COG2270 name: BtlA desc: MFS-type transporter involved in bile tolerance, Atg22 family	integral component of membrane				MNSQKDLKQL...
lpg0264	Q5ZYU7_LEGPH	Uncharacterized protein			Q5ZYU7	unreviewed	mRNA	Q5ZYU7	YP_094318.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 312618 strand: 1 start: 311920	232	26477		N-acetylmuramoyl-L-alanine amidase activity	peptidoglycan catabolic process	accession: cd06583 name: PGRP desc: Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors					MFLQVISYDK...
lpg0265	Q5ZYU6_LEGPH	Multicopper oxidase			Q5ZYU6	unreviewed	mRNA	Q5ZYU6	YP_094319.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 314214 strand: -1 start: 312673	513	58211		copper ion binding oxidoreductase activity		accession: cd13887 name: CuRO_2_MCO_like_2 desc: The second cupredoxin domain of uncharacterized multicopper oxidase accession: cd13896 name: CuRO_3_CopA desc: The third cupredoxin domain of CopA copper resistance protein family accession: cd13865 name: CuRO_1_LCC_like_3 desc: The second cupredoxin domain of uncharacterized multicopper oxidase accession: COG2132 name: SufI desc: Multicopper oxidase with three cupredoxin domains	integral component of membrane				MTNTTDFYSI...
lpg0266	Q5ZYU5_LEGPH	Uncharacterized protein			Q5ZYU5	unreviewed	mRNA	Q5ZYU5	YP_094320.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 314877 strand: 1 start: 314443	144	15661									MKRIFLISII...
lpg0267	Q5ZYU4_LEGPH	Magnesium and cobalt transport protein CorA	corA		Q5ZYU4	unreviewed	mRNA	Q5ZYU4	YP_094321.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 315944 strand: -1 start: 314892	350	40740		metal ion transmembrane transporter activity		accession: cl00459 name: MIT_CorA-like super family desc: metal ion transporter CorA-like divalent cation transporter superfamily	integral component of membrane plasma membrane				MSISFKSPIL...
lpg0268	Q5ZYU3_LEGPH	Uncharacterized protein			Q5ZYU3	unreviewed	mRNA	Q5ZYU3	YP_094322.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 316723 strand: 1 start: 316127	198	23148				accession: pfam13023 name: HD_3 desc: HD domain HD domains are metal dependent phosphohydrolases.					MNQDMEKIEK...
lpg0269	Q5ZYU2_LEGPH	Uncharacterized protein			Q5ZYU2	unreviewed	mRNA	Q5ZYU2	YP_094323.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 318363 strand: 1 start: 316801	520	57630				accession: cl21455 name: P-loop_NTPase super family desc: P-loop containing Nucleoside Triphosphate Hydrolases accession: cl14615 name: PI-PLCc_GDPD_SF super family desc: Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases					MVNQNESSIL...
lpg0270	Q5ZYU1_LEGPH	Nicotinate phosphoribosyltransferase		6.3.4.21	Q5ZYU1	unreviewed	mRNA	Q5ZYU1	YP_094324.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 319848 strand: 1 start: 318430	472	53720	Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.	ligase activity nicotinate phosphoribosyltransferase activity nicotinate-nucleotide diphosphorylase (carboxylating) activity	NAD biosynthetic process nicotinate nucleotide salvage	accession: cd01570 name: NAPRTase_A desc: Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. accession: PRK09243 name: PRK09243 desc: nicotinate phosphoribosyltransferase					MTRIYMINIT...
lpg0271	Q5ZYU0_LEGPH	Bifunctional pyrazinamidase/nicotinamidase	pncA		Q5ZYU0	unreviewed	mRNA	Q5ZYU0	YP_094325.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 320473 strand: 1 start: 319832	213	23751		catalytic activity	metabolic process	accession: cd01011 name: nicotinamidase desc: Nicotinamidase/pyrazinamidase (PZase).					MNTQDNFMKT...
lpg0272	Q5ZYT9_LEGPH	Cysteine transferase			Q5ZYT9	unreviewed	mRNA	Q5ZYT9	YP_094326.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 320939 strand: -1 start: 320556	127	14618		transferase activity		accession: cd08351 name: ChaP_like desc: ChaP, an enzyme involved in the biosynthesis of the antitumor agent chartreusin (cha)					MSIQLNHTIV...
lpg0273	Q5ZYT8_LEGPH	Major facilitator superfamily transporter			Q5ZYT8	unreviewed	mRNA	Q5ZYT8	YP_094327.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 322180 strand: -1 start: 320939	413	44935			transmembrane transport	accession: cd06174 name: MFS desc: Major Facilitator Superfamily (MFS)	integral component of membrane				MLIVKTILIM...
lpg0274	Q5ZYT7_LEGPH	Transcriptional regulator, LysR family			Q5ZYT7	unreviewed	mRNA	Q5ZYT7	YP_094328.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 323134 strand: 1 start: 322271	287	32858		DNA binding transcription factor activity, sequence-specific DNA binding	transcription, DNA-templated	accession: cd08422 name: PBP2_CrgA_like desc: The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA accession: pfam00126 name: HTH_1 desc: Bacterial regulatory helix-turn-helix protein, lysR family accession: COG0583 name: LysR desc: DNA-binding transcriptional regulator, LysR family [Transcription]					MGKFDQITYF...
lpg0275	Q5ZYT6_LEGPH	SdbA			Q5ZYT6	unreviewed	mRNA	Q5ZYT6	YP_094329.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 326904 strand: 1 start: 323554	1116	127191				accession: pfam00561 name: Abhydrolase_1 desc: alpha/beta hydrolase fold This catalytic domain is found in a very wide range of enzymes.					MHKKYNYYSL...
lpg0276	Q5ZYT5_LEGPH	Ras GEF	legG2		Q5ZYT5	unreviewed	mRNA	Q5ZYT5	YP_094330.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 328561 strand: 1 start: 327062	499	58533		guanyl-nucleotide exchange factor activity	small GTPase mediated signal transduction	accession: pfam00617 name: RasGEF desc: RasGEF domain Guanine nucleotide exchange factor for Ras-like small GTPases.	intracellular				MINKSRLLSL...
lpg0277	Q5ZYT4_LEGPH	Sensory box protein, GGDEF family protein, LssE			Q5ZYT4	unreviewed	mRNA	Q5ZYT4	YP_094331.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 330849 strand: -1 start: 328627	740	84492			phosphorelay signal transduction system	accession: cd01948 name: EAL desc: EAL domain. This domain is found in diverse bacterial signaling proteins. accession: cd01949 name: GGDEF desc: Diguanylate-cyclase (DGC) or GGDEF domain accession: COG0784 name: CheY desc: CheY chemotaxis protein or a CheY-like REC (receiver) domain [Signal transduction mechanisms] accession: smart00091 name: PAS desc: PAS domain PAS motifs appear in archaea, eubacteria and eukarya.	intracellular			position: 87 desc: 4-aspartylphosphate	MSTESFRILV...
lpg0278	Q5ZYT3_LEGPH	Sensor histidine kinase	fixL	2.7.3.-	Q5ZYT3	unreviewed	mRNA	Q5ZYT3	YP_094332.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 332267 strand: -1 start: 330852	471	53519		ATP binding kinase activity		accession: pfam02518 name: HATPase_c desc: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase accession: cd00130 name: PAS desc: PAS domain PAS motifs appear in archaea, eubacteria and eukarya. accession: pfam08447 name: PAS_3 desc: PAS fold					MTEMHRLLQR...
lpg0279	Q5ZYT2_LEGPH	Uncharacterized protein			Q5ZYT2	unreviewed	mRNA	Q5ZYT2	YP_094333.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 333456 strand: -1 start: 332290	388	42424				accession: smart00897 name: FIST desc: FIST N domain The FIST N domain is a novel sensory domain accession: pfam10442 name: FIST_C desc: FIST C domain The FIST C domain is a novel sensory domain					MMKIESFQYI...
lpg0280	Q5ZYT1_LEGPH	Transcriptional regulator, LysR family			Q5ZYT1	unreviewed	mRNA	Q5ZYT1	YP_094334.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 334503 strand: -1 start: 333622	293	33566		DNA binding transcription factor activity, sequence-specific DNA binding	transcription, DNA-templated	accession: cd05466 name: PBP2_LTTR_substrate desc: The substrate binding domain of LysR-type transcriptional regulators (LTTRs) accession: pfam00126 name: HTH_1 desc: Bacterial regulatory helix-turn-helix protein, lysR family accession: COG0583 name: LysR desc: DNA-binding transcriptional regulator, LysR family [Transcription]					MDIRDIKSFL...
lpg0281	Q5ZYT0_LEGPH	Amino acid transporter			Q5ZYT0	unreviewed	mRNA	Q5ZYT0	YP_094335.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 335909 strand: -1 start: 334725	394	43021		amino acid transmembrane transporter activity		accession: cl00456 name: SLC5-6-like_sbd super family desc: Solute carrier families 5 and 6-like solute binding domain	integral component of membrane				MHLKRTLSLT...
lpg0282	Q5ZYS9_LEGPH	Uncharacterized protein			Q5ZYS9	unreviewed	mRNA	Q5ZYS9	YP_094336.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 336753 strand: -1 start: 335977	258	29389				accession: pfam13847 name: Methyltransf_31 desc: Methyltransferase domain This family appears to be have methyltransferase activity. accession: TIGR02072 name: BioC desc: malonyl-acyl carrier protein O-methyltransferase BioC					MSRREWPAND...
lpg0283	Q5ZYS8_LEGPH	Formate dehydrogenase		1.2.1.2	Q5ZYS8	unreviewed	mRNA	Q5ZYS8	YP_094337.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 338172 strand: 1 start: 336961	403	44456	Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.	formate dehydrogenase (NAD+) activity NAD binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	formate catabolic process	accession: cd05302 name: FDH desc: NAD-dependent Formate Dehydrogenase (FDH) accession: PRK07574 name: PRK07574 desc: formate dehydrogenase Provisional	cytoplasm				MFSQSQQKIV...
lpg0284	Q5ZYS7_LEGPH	Uncharacterized protein			Q5ZYS7	unreviewed	mRNA	Q5ZYS7	YP_094338.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 339402 strand: -1 start: 338278	374	43392									MFTKSCAKAT...
lpg0285	Q5ZYS6_LEGPH	Uncharacterized protein			Q5ZYS6	unreviewed	mRNA	Q5ZYS6	YP_094339.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 340322 strand: 1 start: 339639	227	25847									MVIIGILMSK...
lpg0286	Q5ZYS5_LEGPH	Oxidoreductase, short chain dehydrogenase/reductase family		1.-.-.-	Q5ZYS5	unreviewed	mRNA	Q5ZYS5	YP_094340.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 341203 strand: 1 start: 340355	282	31671		oxidoreductase activity		accession: cl21454 name: NADB_Rossmann super family desc: Rossmann-fold NAD(P)(+)-binding proteins accession: COG4221 name: YdfG desc: NADP-dependent 3-hydroxy acid dehydrogenase YdfG [Energy production and conversion]					MLLFLFKFWF...
lpg0287	EFP_LEGPH	Elongation factor P	efp		Q5ZYS4	reviewed	mRNA	Q5ZYS4	YP_094341.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 342622 strand: -1 start: 342005	189	20887	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.	translation elongation factor activity		accession: pfam09285 name: Elong-fact-P_C desc: Elongation factor P, C-terminal accession: cd04470 name: S1_EF-P_repeat_1 desc: S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain accession: pfam08207 name: EFP_N desc: Elongation factor P (EF-P) KOW-like domain accession: PRK00529 name: PRK00529 desc: elongation factor P	cytoplasm			position: 34 desc: N6-(3,6-diaminohexanoyl)-5-hydroxylysine	MAVYSTNEFK...
lpg0288	Q5ZYS3_LEGPH	L-lysine 2,3-aminomutase, radical SAM domain protein			Q5ZYS3	unreviewed	mRNA	Q5ZYS3	YP_094342.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 343626 strand: 1 start: 342646	326	36732		4 iron, 4 sulfur cluster binding catalytic activity metal ion binding		accession: cl23776 name: EFP_modif_epmB super family desc: EF-P beta-lysylation protein EpmB Members of this radical SAM protein subfamily		pyridoxal 5'-phosphate		position: 322 desc: N6-(pyridoxal phosphate)lysine	MRDTSLSWQK...
lpg0289	Q5ZYS2_LEGPH	Polyphosphate kinase	ppk	2.7.4.1	Q5ZYS2	unreviewed	mRNA	Q5ZYS2	YP_094343.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 345779 strand: -1 start: 343695	694	79781	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).	ATP binding metal ion binding polyphosphate kinase activity	polyphosphate biosynthetic process	accession: cd09168 name: PLDc_PaPPK1_C2_like desc: Catalytic C-terminal domain accession: cl15239 name: PLDc_SF super family desc: Catalytic domain of phospholipase D superfamily proteins accession: pfam02503 name: PP_kinase desc: Polyphosphate kinase middle domain accession: pfam13089 name: PP_kinase_N desc: Polyphosphate kinase N-terminal domain accession: PRK05443 name: PRK05443 desc: polyphosphate kinase Provisional	polyphosphate kinase complex	Mg(2+)			MEFLMDTTLD...
lpg0290	Q5ZYS1_LEGPH	Lipoprotein			Q5ZYS1	unreviewed	mRNA	Q5ZYS1	YP_094344.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 347013 strand: -1 start: 345808	401	44567			lipid metabolic process	accession: cl11396 name: Patatin_and_cPLA2 super family desc: Patatins and Phospholipases Patatin-like phospholipase.					MKRIFFVVFL...
lpg0291	Q5ZYS0_LEGPH	Chromate transport protein			Q5ZYS0	unreviewed	mRNA	Q5ZYS0	YP_094345.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 347622 strand: -1 start: 347089	177	19339		chromate transmembrane transporter activity		accession: pfam02417 name: Chromate_transp desc: Chromate transporter Members of this family probably act as chromate transporters	integral component of membrane				MIKTFIEIIY...
lpg0292	Q5ZYR9_LEGPH	Uncharacterized protein			Q5ZYR9	unreviewed	mRNA	Q5ZYR9	YP_094346.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 348296 strand: -1 start: 347619	225	26072									MPKQIKSSSV...
lpg0293	Q5ZYR8_LEGPH	Long chain acyl-CoA dehydrogenase		1.3.99.-	Q5ZYR8	unreviewed	mRNA	Q5ZYR8	YP_094347.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 350853 strand: 1 start: 348415	812	91150		acyl-CoA dehydrogenase activity flavin adenine dinucleotide binding	fatty acid beta-oxidation using acyl-CoA dehydrogenase	accession: pfam09317 name: DUF1974 desc: Domain of unknown function (DUF1974) accession: cd00567 name: ACAD desc: Acyl-CoA dehydrogenase accession: pfam02771 name: Acyl-CoA_dh_N desc: Acyl-CoA dehydrogenase, N-terminal domain accession: PRK13026 name: PRK13026 desc: acyl-CoA dehydrogenase	integral component of membrane				MAIVFFLIYL...
lpg0294	Q5ZYR7_LEGPH	Uncharacterized protein			Q5ZYR7	unreviewed	mRNA	Q5ZYR7	YP_094348.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 351659 strand: 1 start: 350967	230	25520									MPKYTLPTRD...
lpg0295	Q5ZYR6_LEGPH	Mannose-1-phosphate guanyltransferase			Q5ZYR6	unreviewed	mRNA	Q5ZYR6	YP_094349.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 352358 strand: -1 start: 351696	220	24336		nucleotidyltransferase activity	biosynthetic process	accession: cd06422 name: NTP_transferase_like_1 desc: NTP_transferase_like_1 is a member of the nucleotidyl transferase family accession: COG1208 name: GCD1 desc: NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis					MKTAMILAAG...
lpg0296	Q5ZYR5_LEGPH	Hypothetical phosphotransferase			Q5ZYR5	unreviewed	mRNA	Q5ZYR5	YP_094350.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 353401 strand: -1 start: 352355	348	40823		transferase activity		accession: cl21453 name: PKc_like super family desc: Protein Kinases, catalytic domain accession: pfam01636 name: APH desc: Phosphotransferase enzyme family					MKLLFIKMGV...
lpg0297	LPTD_LEGPH	LPS-assembly protein LptD	ostA		Q5ZYR4	reviewed	mRNA	Q5ZYR4	YP_094351.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 356094 strand: 1 start: 353425	839	95958	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.		Gram-negative-bacterium-type cell outer membrane assembly lipopolysaccharide transport response to organic substance	accession: pfam04453 name: OstA_C desc: Organic solvent tolerance protein accession: cl21541 name: OstA super family desc: OstA-like protein This family of proteins are mostly uncharacterized. accession: COG1452 name: LptD desc: LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	cell outer membrane				MAIGITACVL...
lpg0298	SURA_LEGPH	Chaperone SurA	surA	5.2.1.8	Q5ZYR3	reviewed	mRNA	Q5ZYR3	YP_094352.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 357559 strand: 1 start: 356219	429	48492	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.	peptide binding peptidyl-prolyl cis-trans isomerase activity	chaperone mediated protein folding requiring cofactor Gram-negative-bacterium-type cell outer membrane assembly maintenance of stationary phase protein stabilization	accession: cl21568 name: SurA_N_3 super family desc: SurA N-terminal domain This domain is found at the N-terminus of the chaperone SurA. accession: pfam13616 name: Rotamase_3 desc: PPIC-type PPIASE domain Rotamases increase the rate of protein folding accession: pfam00639 name: Rotamase desc: PPIC-type PPIASE domain Rotamases increase the rate of protein folding	outer membrane-bounded periplasmic space				MFKRIALVCA...
lpg0299	Q3V872_LEGPH	4-hydroxythreonine-4-phosphate dehydrogenase	pdxA	1.1.1.262	Q3V872	unreviewed	mRNA	Q3V872	YP_094353.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 358530 strand: 1 start: 357556	324	34709	Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).	4-hydroxythreonine-4-phosphate dehydrogenase activity cobalt ion binding magnesium ion binding NAD binding zinc ion binding	pyridoxal phosphate biosynthetic process pyridoxine biosynthetic process	accession: TIGR00557 name: pdxA desc: 4-hydroxythreonine-4-phosphate dehydrogenase	cytoplasm	Zn(2+)			MNPLLISSGE...
lpg0300	Q5ZYR2_LEGPH	Dihydrofolate reductase		1.5.1.3	Q5ZYR2	unreviewed	mRNA	Q5ZYR2	YP_094354.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 359023 strand: 1 start: 358532	163	18240	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.	dihydrofolate reductase activity NADP binding	glycine biosynthetic process nucleotide biosynthetic process one-carbon metabolic process tetrahydrofolate biosynthetic process	accession: pfam00186 name: DHFR_1 desc: Dihydrofolate reductase					MSLISLIAAI...
lpg0301	Q5ZYR1_LEGPH	Uncharacterized protein			Q5ZYR1	unreviewed	mRNA	Q5ZYR1	YP_094355.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 359575 strand: -1 start: 359030	181	20683				accession: cl02743 name: DM9 super family desc: Repeats found in Drosophila proteins accession: cl02743 name: DM9 super family desc: Repeats found in Drosophila proteins accession: pfam11901 name: DUF3421 desc: Protein of unknown function (DUF3421)					MSKLVYLLLM...
lpg0302	NaN	16S ribosomal RNA				NaN	rRNA				end: 361336 strand: 1 start: 359862											...
lpg0303	NaN	tRNA-Ala				NaN	tRNA				end: 361553 strand: 1 start: 361478											...
lpg0304	NaN	23S ribosomal RNA				NaN	rRNA				end: 364621 strand: 1 start: 361720											...
lpg0305	Q5ZY06_LEGPH	Uncharacterized protein			Q5ZY06	unreviewed	mRNA	Q5ZY06	YP_094356.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 363300 strand: -1 start: 362950	116	13147									MASSFSWKPG...
lpg0306	Q5ZY05_LEGPH	Uncharacterized protein			Q5ZY05	unreviewed	mRNA	Q5ZY05	YP_094357.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 364132 strand: -1 start: 363791	113	12320									MALPFRTTGS...
lpg0307	Q5ZY04_LEGPH	Hypothetical CTC00065, TC0129			Q5ZY04	unreviewed	mRNA	Q5ZY04	YP_094358.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 364190 strand: -1 start: 363909	93	10362									MNSWAVSACY...
lpg0309	NaN	5S ribosomal RNA				NaN	rRNA				end: 364840 strand: 1 start: 364723											...
lpg0310	NaN	tRNA-Thr				NaN	tRNA				end: 365021 strand: 1 start: 364946											...
lpg0311	NaN	tRNA-Tyr				NaN	tRNA				end: 365178 strand: 1 start: 365094											...
lpg0312	NaN	tRNA-Gly				NaN	tRNA				end: 365272 strand: 1 start: 365199											...
lpg0313	NaN	tRNA-Thr				NaN	tRNA				end: 365400 strand: 1 start: 365325											...
lpg0314	EFTU_LEGPH	Elongation factor Tu	tuf2		Q5ZYP5	reviewed	mRNA	Q5ZYP5	YP_094359.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 366625 strand: 1 start: 365435	396	43179	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.	GTP binding GTPase activity translation elongation factor activity		accession: cd01884 name: EF_Tu desc: Elongation Factor Tu (EF-Tu) GTP-binding proteins EF-Tu subfamily. accession: cd03707 name: EFTU_III desc: Domain III of Elongation Factor (EF) Tu accession: cd03697 name: EFTU_II desc: Domain II of elongation factor Tu accession: PRK00049 name: PRK00049 desc: elongation factor Tu	cytoplasm				MAKEKFERKK...
lpg0315	NaN	tRNA-Trp				NaN	tRNA				end: 366760 strand: 1 start: 366685											...
lpg0316	Q5ZYQ6_LEGPH	Protein translocase subunit SecE	secE		Q5ZYQ6	unreviewed	mRNA	Q5ZYQ6	YP_094360.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 367145 strand: 1 start: 366774	123	13900	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	intracellular protein transmembrane transport protein secretion protein targeting protein transport by the Sec complex	accession: PRK05740 name: secE desc: preprotein translocase subunit SecE	integral component of membrane intracellular plasma membrane				MKSSNENQGK...
lpg0317	Q5ZYQ5_LEGPH	Transcription termination/antitermination protein NusG	nusG		Q5ZYQ5	unreviewed	mRNA	Q5ZYQ5	YP_094361.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 367696 strand: 1 start: 367142	184	21151	Participates in transcription elongation, termination and antitermination.		DNA-templated transcription, elongation DNA-templated transcription, termination regulation of DNA-templated transcription, elongation transcription antitermination	accession: cd09891 name: NGN_Bact_1 desc: Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1 accession: cd06091 name: KOW_NusG desc: NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus accession: PRK05609 name: nusG desc: transcription antitermination protein NusG					MNMVEENKAK...
lpg0318	RL11_LEGPH	50S ribosomal protein L11	rplK		Q5ZYQ4	reviewed	mRNA	Q5ZYQ4	YP_094362.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 368241 strand: 1 start: 367807	144	15090	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	large ribosomal subunit rRNA binding structural constituent of ribosome	translation	accession: cd00349 name: Ribosomal_L11 desc: Ribosomal protein L11. accession: PRK00140 name: rplK desc: 50S ribosomal protein L11	ribosome				MAKKVEAYIK...
lpg0319	RL1_LEGPH	50S ribosomal protein L1	rplA		Q5ZYQ3	reviewed	mRNA	Q5ZYQ3	YP_094363.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 368946 strand: 1 start: 368251	231	24512	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.	rRNA binding structural constituent of ribosome tRNA binding	regulation of translation translation	accession: PRK05424 name: rplA desc: 50S ribosomal protein L1	large ribosomal subunit				MSKLTKKQKK...
lpg0320	RL10_LEGPH	50S ribosomal protein L10	rplJ		Q5ZYQ2	reviewed	mRNA	Q5ZYQ2	YP_094364.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 369652 strand: 1 start: 369119	177	19321	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.	large ribosomal subunit rRNA binding structural constituent of ribosome	ribosome biogenesis translation	accession: PRK00099 name: rplJ desc: 50S ribosomal protein L10	ribosome				MTLNLAAKKA...
lpg0321	RL7_LEGPH	50S ribosomal protein L7/L12	rplL		Q5ZYQ1	reviewed	mRNA	Q5ZYQ1	YP_094365.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 370063 strand: 1 start: 369683	126	12911	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.	structural constituent of ribosome	translation	accession: cd00387 name: Ribosomal_L7_L12 desc: Ribosomal protein L7/L12. accession: PRK00157 name: rplL desc: 50S ribosomal protein L7/L12	ribosome				MAVSKNEILE...
lpg0322	RPOB_LEGPH	DNA-directed RNA polymerase subunit beta	rpoB	2.7.7.6	Q5ZYQ0	reviewed	mRNA	Q5ZYQ0	YP_094366.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 374261 strand: 1 start: 370155	1368	152719	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA binding DNA-directed RNA polymerase activity ribonucleoside binding	transcription, DNA-templated	accession: cd00653 name: RNA_pol_B_RPB2 desc: RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. ... accession: pfam10385 name: RNA_pol_Rpb2_45 desc: RNA polymerase beta subunit external 1 domain accession: cl24026 name: RNA_pol_Rpb2_2 super family desc: RNA polymerase Rpb2, domain 2 accession: PRK00405 name: rpoB desc: DNA-directed RNA polymerase subunit beta					MAVAEAKPQY...
lpg0323	RPOC_LEGPH	DNA-directed RNA polymerase subunit beta'	rpoC	2.7.7.6	Q5ZYP9	reviewed	mRNA	Q5ZYP9	YP_094367.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 378555 strand: 1 start: 374308	1401	155654	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA binding DNA-directed RNA polymerase activity	transcription, DNA-templated	accession: cd01609 name: RNAP_beta'_N desc: Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain accession: cd02655 name: RNAP_beta'_C desc: Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain accession: cl11429 name: RNAP_largest_subunit_C super family desc: Largest subunit of RNA polymerase (RNAP), C-terminal domain accession: PRK00566 name: PRK00566 desc: DNA-directed RNA polymerase subunit beta' Provisional					MSDLLGILKQ...
lpg0324	RS12_LEGPH	30S ribosomal protein S12	rpsL		Q5ZYP8	reviewed	mRNA	Q5ZYP8	YP_094368.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 379049 strand: 1 start: 378669	126	14071	With S4 and S5 plays an important role in translational accuracy. Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	rRNA binding structural constituent of ribosome tRNA binding	translation	accession: PRK05163 name: rpsL desc: 30S ribosomal protein S12	small ribosomal subunit			position: 89 desc: 3-methylthioaspartic acid	MATINQLVRK...
lpg0325	RS7_LEGPH	30S ribosomal protein S7	rpS7		Q5ZYP7	reviewed	mRNA	Q5ZYP7	YP_094369.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 379597 strand: 1 start: 379070	175	19791	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.	rRNA binding structural constituent of ribosome tRNA binding	translation	accession: PRK05302 name: PRK05302 desc: 30S ribosomal protein S7	small ribosomal subunit				MPRRREVPKR...
lpg0326	EFG_LEGPH	Elongation factor G	fusA		Q5ZYP6	reviewed	mRNA	Q5ZYP6	YP_094370.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 381696 strand: 1 start: 379612	694	77026	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	GTP binding GTPase activity translation elongation factor activity		accession: cd01886 name: EF-G desc: Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling accession: cd01434 name: EFG_mtEFG1_IV desc: EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor accession: smart00838 name: EFG_C desc: Elongation factor G C-terminus accession: cd04088 name: EFG_mtEFG_II desc: Domain II of bacterial elongation factor G and C-terminal domain of mitochondrial Elongation factors G1 (mtEFG1) and G2 (mtEFG2) accession: cd16262 name: EFG_III desc: Domain III of Elongation Factor G (EFG) accession: PRK00007 name: PRK00007 desc: elongation factor G	cytoplasm				MATPLKLYRN...
lpg0327	EFTU_LEGPH	Elongation factor Tu	tufB		Q5ZYP5	reviewed	mRNA	Q5ZYP5	YP_094371.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 382907 strand: 1 start: 381717	396	43179	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.	GTP binding GTPase activity translation elongation factor activity		accession: cd01884 name: EF_Tu desc: Elongation Factor Tu (EF-Tu) GTP-binding proteins EF-Tu subfamily. accession: cd03707 name: EFTU_III desc: Domain III of Elongation Factor (EF) Tu accession: cd03697 name: EFTU_II desc: Domain II of elongation factor Tu accession: PRK00049 name: PRK00049 desc: elongation factor Tu	cytoplasm				MAKEKFERKK...
lpg0328	RS10_LEGPH	30S ribosomal protein S10	rpsJ		Q5ZYP4	reviewed	mRNA	Q5ZYP4	YP_094372.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 383230 strand: 1 start: 382913	105	11938	Involved in the binding of tRNA to the ribosomes.	structural constituent of ribosome tRNA binding	translation	accession: PRK00596 name: rpsJ desc: 30S ribosomal protein S10	ribosome				MSSNQNIKIR...
lpg0329	RL3_LEGPH	50S ribosomal protein L3	rplC		Q5ZYP3	reviewed	mRNA	Q5ZYP3	YP_094373.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 383915 strand: 1 start: 383268	216	22896	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	rRNA binding structural constituent of ribosome	translation	accession: PRK00001 name: rplC desc: 50S ribosomal protein L3	ribosome			position: 152 desc: N5-methylglutamine	MMIGLLGRKI...
lpg0330	RL4_LEGPH	50S ribosomal protein L4	rplD		Q5ZYP2	reviewed	mRNA	Q5ZYP2	YP_094374.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 384520 strand: 1 start: 383912	202	22836	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel.	rRNA binding structural constituent of ribosome	translation	accession: PRK05319 name: rplD desc: 50S ribosomal protein L4 Provisional	ribosome				MMEITTIDTK...
lpg0331	RL23_LEGPH	50S ribosomal protein L23	rplW		Q5ZYP1	reviewed	mRNA	Q5ZYP1	YP_094375.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 384813 strand: 1 start: 384535	98	11259	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.	nucleotide binding rRNA binding structural constituent of ribosome	translation	accession: PRK05738 name: rplW desc: 50S ribosomal protein L23	ribosome				MNAERLMMVL...
lpg0332	RL2_LEGPH	50S ribosomal protein L2	rplB		Q5ZYP0	reviewed	mRNA	Q5ZYP0	YP_094376.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 385652 strand: 1 start: 384825	275	30091	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.	rRNA binding structural constituent of ribosome transferase activity	translation	accession: pfam03947 name: Ribosomal_L2_C desc: Ribosomal Proteins L2, C-terminal domain accession: pfam00181 name: Ribosomal_L2 desc: Ribosomal Proteins L2, RNA binding domain accession: PRK09374 name: rplB desc: 50S ribosomal protein L2	large ribosomal subunit				MALLKSKPTS...
lpg0333	Q5ZYN9_LEGPH	Uncharacterized protein			Q5ZYN9	unreviewed	mRNA	Q5ZYN9	YP_094377.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 386176 strand: -1 start: 385874	100	10747									MPTFRSSISA...
lpg0334	RL22_LEGPH	50S ribosomal protein L22	rplV		Q5ZYN8	reviewed	mRNA	Q5ZYN8	YP_094378.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 386294 strand: 1 start: 385959	112	12152	This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	rRNA binding structural constituent of ribosome	translation	accession: PRK00565 name: rplV desc: 50S ribosomal protein L22	large ribosomal subunit				MMEVTAKLKG...
lpg0335	RS3_LEGPH	30S ribosomal protein S3	rpsC		Q5ZYN7	reviewed	mRNA	Q5ZYN7	YP_094379.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 386953 strand: 1 start: 386297	218	24117	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.	mRNA binding rRNA binding structural constituent of ribosome	translation	accession: pfam00189 name: Ribosomal_S3_C desc: Ribosomal protein S3, C-terminal domain accession: cd02412 name: 30S_S3_KH desc: K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. accession: PRK00310 name: rpsC desc: 30S ribosomal protein S3	small ribosomal subunit				MGQKVNPIGI...
lpg0336	RL16_LEGPH	50S ribosomal protein L16	rplP		Q5ZYN6	reviewed	mRNA	Q5ZYN6	YP_094380.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 387383 strand: 1 start: 386970	137	15762	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.	rRNA binding structural constituent of ribosome tRNA binding	translation	accession: PRK09203 name: rplP desc: 50S ribosomal protein L16	ribosome				MLQPKRTKYR...
lpg0337	RL29_LEGPH	50S ribosomal protein L29	rpmC		Q5ZYN5	reviewed	mRNA	Q5ZYN5	YP_094381.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 387577 strand: 1 start: 387383	64	7373		structural constituent of ribosome	translation	accession: PRK00306 name: PRK00306 desc: 50S ribosomal protein L29	ribosome				MKKIDELRNM...
lpg0338	RS17_LEGPH	30S ribosomal protein S17	rpsQ		Q5ZYN4	reviewed	mRNA	Q5ZYN4	YP_094382.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 387833 strand: 1 start: 387579	84	9637	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	rRNA binding structural constituent of ribosome	translation	accession: PRK05610 name: rpsQ desc: 30S ribosomal protein S17	ribosome				MSTNSESNAR...
lpg0339	RL14_LEGPH	50S ribosomal protein L14	rplN		Q5ZYN3	reviewed	mRNA	Q5ZYN3	YP_094383.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 388287 strand: 1 start: 387922	121	13388	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.	rRNA binding structural constituent of ribosome	translation	accession: PRK05483 name: rplN desc: 50S ribosomal protein L14	large ribosomal subunit				MIQMQTVLEV...
lpg0340	RL24_LEGPH	50S ribosomal protein L24	rplX		Q5ZYN2	reviewed	mRNA	Q5ZYN2	YP_094384.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 388629 strand: 1 start: 388300	109	12054	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	rRNA binding structural constituent of ribosome	translation	accession: PRK00004 name: rplX desc: 50S ribosomal protein L24	ribosome				MKRIKSGDEV...
lpg0341	RL5_LEGPH	50S ribosomal protein L5	rplE		Q5ZYN1	reviewed	mRNA	Q5ZYN1	YP_094385.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 389196 strand: 1 start: 388645	186	21312	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	rRNA binding structural constituent of ribosome tRNA binding	translation	accession: pfam00673 name: Ribosomal_L5_C desc: ribosomal L5P family C-terminus This region is found associated with pfam00281. accession: pfam00281 name: Ribosomal_L5 desc: Ribosomal protein L5 accession: PRK00010 name: rplE desc: 50S ribosomal protein L5	ribosome				MIEMARLKEF...
lpg0342	RS14_LEGPH	30S ribosomal protein S14	rpsN		Q5ZYN0	reviewed	mRNA	Q5ZYN0	YP_094386.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 389511 strand: 1 start: 389209	100	11755	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.	metal ion binding rRNA binding structural constituent of ribosome	translation	accession: cl00355 name: Ribosomal_S14 super family desc: Ribosomal protein S14p/S29e	ribosome	Zn(2+)			MAKKSMLMRE...
lpg0343	RS8_LEGPH	30S ribosomal protein S8	rpsH		Q5ZYM9	reviewed	mRNA	Q5ZYM9	YP_094387.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 389929 strand: 1 start: 389534	131	14681	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.	rRNA binding structural constituent of ribosome	translation	accession: PRK00136 name: rpsH desc: 30S ribosomal protein S8	ribosome				MSMHDPIADM...
lpg0344	RL6_LEGPH	50S ribosomal protein L6	rplF		Q5ZYM8	reviewed	mRNA	Q5ZYM8	YP_094388.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 390486 strand: 1 start: 389947	179	19432	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.	rRNA binding structural constituent of ribosome	translation	accession: pfam00347 name: Ribosomal_L6 desc: Ribosomal protein L6 accession: pfam00347 name: Ribosomal_L6 desc: Ribosomal protein L6 accession: PRK05498 name: rplF desc: 50S ribosomal protein L6	ribosome				MSRVAKAPVI...
lpg0345	RL18_LEGPH	50S ribosomal protein L18	rplR		Q5ZYM7	reviewed	mRNA	Q5ZYM7	YP_094389.2	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 390856 strand: 1 start: 390497	119	13007	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	rRNA binding structural constituent of ribosome	translation	accession: PRK05593 name: rplR desc: 50S ribosomal protein L18	ribosome				MNKQNARHRR...
lpg0346	RS5_LEGPH	30S ribosomal protein S5	rpsE		Q5ZYM6	reviewed	mRNA	Q5ZYM6	YP_094390.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 391372 strand: 1 start: 390866	168	17697	With S4 and S12 plays an important role in translational accuracy. Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.	rRNA binding structural constituent of ribosome	translation	accession: pfam00333 name: Ribosomal_S5 desc: Ribosomal protein S5, N-terminal domain accession: pfam03719 name: Ribosomal_S5_C desc: Ribosomal protein S5, C-terminal domain accession: PRK00550 name: rpsE desc: 30S ribosomal protein S5	small ribosomal subunit				MSFDELPKSD...
lpg0347	RL30_LEGPH	50S ribosomal protein L30	rpmD		Q5ZYM5	reviewed	mRNA	Q5ZYM5	YP_094391.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 391560 strand: 1 start: 391375	61	6567		structural constituent of ribosome	translation	accession: PRK05611 name: rpmD desc: 50S ribosomal protein L30	large ribosomal subunit				MGKKIKITLV...
lpg0348	RL15_LEGPH	50S ribosomal protein L15	rplO		Q5ZYM4	reviewed	mRNA	Q5ZYM4	YP_094392.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 391994 strand: 1 start: 391560	144	15344	Binds to the 23S rRNA.	rRNA binding structural constituent of ribosome	translation	accession: PRK05592 name: rplO desc: 50S ribosomal protein L15	large ribosomal subunit				MNLNTLSPDP...
lpg0349	Q5ZYM3_LEGPH	Protein translocase subunit SecY	secY		Q5ZYM3	unreviewed	mRNA	Q5ZYM3	YP_094393.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 393325 strand: 1 start: 391991	444	48981	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.		intracellular protein transmembrane transport protein targeting protein transport by the Sec complex	accession: pfam00344 name: ecY desc: SecY translocase accession: PRK09204 name: secY desc: preprotein translocase subunit SecY	integral component of membrane intracellular plasma membrane				MTMKNQKHNG...
lpg0350	RL36_LEGPH	50S ribosomal protein L36	rpmJ		Q5ZYM2	reviewed	mRNA	Q5ZYM2	YP_094394.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 393455 strand: 1 start: 393342	37	4310		structural constituent of ribosome	translation	accession: PRK00465 name: rpmJ desc: 50S ribosomal protein L36	ribosome				MKVRASVKRI...
lpg0351	RS13_LEGPH	30S ribosomal protein S13	rpsM		Q5ZYM1	reviewed	mRNA	Q5ZYM1	YP_094395.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 393889 strand: 1 start: 393533	118	13134	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.	rRNA binding structural constituent of ribosome tRNA binding	translation	accession: PRK05179 name: rpsM desc: 30S ribosomal protein S13 accession: COG0099 name: RpsM desc: Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]	ribosome				MARIAGVNIP...
lpg0352	RS11_LEGPH	30S ribosomal protein S11	rpsK		Q5ZYM0	reviewed	mRNA	Q5ZYM0	YP_094396.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 394311 strand: 1 start: 393913	132	14366	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.	rRNA binding structural constituent of ribosome	translation	accession: PRK05309 name: desc: 30S ribosomal protein S11	ribosome				MAITKSKQQK...
lpg0353	RS4_LEGPH	30S ribosomal protein S4	rpsD		Q5ZYL9	reviewed	mRNA	Q5ZYL9	YP_094397.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 394948 strand: 1 start: 394328	206	23261	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. With S5 and S12 plays an important role in translational accuracy.	rRNA binding structural constituent of ribosome	translation	accession: pfam00163 name: Ribosomal_S4 desc: Ribosomal protein S4/S9 N-terminal domain accession: cd00165 name: S4 desc: S4/Hsp/ tRNA synthetase RNA-binding domain accession: PRK05327 name: rpsD desc: 30S ribosomal protein S4	small ribosomal subunit				MARYLGPKCK...
lpg0354	RPOA_LEGPH	DNA-directed RNA polymerase subunit alpha	rpoA	2.7.7.6	Q5ZYL8	reviewed	mRNA	Q5ZYL8	YP_094398.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 395959 strand: 1 start: 394967	330	36761	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA binding DNA-directed RNA polymerase activity	transcription, DNA-templated	accession: cd06928 name: RNAP_alpha_NTD desc: N-terminal domain of the Alpha subunit of Bacterial RNA polymerase accession: pfam03118 name: RNA_pol_A_CTD desc: Bacterial RNA polymerase, alpha chain C terminal domain accession: PRK05182 name: PRK05182 desc: DNA-directed RNA polymerase subunit alpha Provisional					MYTEINEMLT...
lpg0355	RL17_LEGPH	50S ribosomal protein L17	rplQ		Q5ZYL7	reviewed	mRNA	Q5ZYL7	YP_094399.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 396361 strand: 1 start: 395978	127	14450		structural constituent of ribosome	translation	accession: PRK05591 name: rplQ desc: 50S ribosomal protein L17	ribosome				MRHRNSGRSF...
lpg0356	Q5ZYL6_LEGPH	Single-stranded DNA-binding protein	ssb		Q5ZYL6	unreviewed	mRNA	Q5ZYL6	YP_094400.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 396917 strand: -1 start: 396429	162	17975	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.	single-stranded DNA binding	DNA recombination DNA repair DNA replication	accession: cl09930 name: RPA_2b-aaRSs_OBF_like super family desc: Replication protein A, class 2b aminoacyl-tRNA synthetases accession: COG0629 name: Ssb desc: Single-stranded DNA-binding protein [Replication, recombination and repair]					MISMARGINK...
lpg0357	Q5ZYL5_LEGPH	Major facilitator family transporter			Q5ZYL5	unreviewed	mRNA	Q5ZYL5	YP_094401.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 398359 strand: -1 start: 396992	455	50345			transmembrane transport	accession: cd06174 name: MFS desc: The Major Facilitator Superfamily (MFS) accession: pfam07690 name: MFS_1 desc: Major Facilitator Superfamily	integral component of membrane				MKYSWNKTVF...
lpg0358	Q5ZYL4_LEGPH	Glucose-1-dehydrogenase			Q5ZYL4	unreviewed	mRNA	Q5ZYL4	YP_094402.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 399279 strand: 1 start: 398521	252	26884				accession: cd05359 name: ChcA_like_SDR_c desc: 1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs accession: PRK08063 name: PRK08063 desc: enoyl-(acyl carrier protein) reductase Provisional					MSSLVFSGKV...
lpg0359	Q5ZYL3_LEGPH	Acyl carrier protein	acpP		Q5ZYL3	unreviewed	mRNA	Q5ZYL3	YP_094403.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 399763 strand: 1 start: 399350	137	15319	Carrier of the growing fatty acid chain in fatty acid biosynthesis.	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process		accession: PRK00982 name: acpP desc: acyl carrier protein Provisional	cytoplasm			position: 39 desc: O-(pantetheine 4'-phosphoryl)serine	MNVAEVYPKV...
lpg0360	Q5ZYL2_LEGPH	3-hydroxymyristoyl/3-hydroxydecanoyl-(Acyl carrier protein) dehydratases	fabA	4.2.1.-	Q5ZYL2	unreviewed	mRNA	Q5ZYL2	YP_094404.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 400659 strand: 1 start: 399760	299	33781		lyase activity		accession: cl00509 name: hot_dog super family desc: The hotdog fold was initially identified in the E. coli FabA accession: cl00509 name: hot_dog super family desc: The hotdog fold was initially identified in the E. coli FabA					MMRFLFVDRI...
lpg0361	Q5ZYL1_LEGPH	3-oxoacyl-[acyl-carrier-protein] synthase 2	fabF	2.3.1.179	Q5ZYL1	unreviewed	mRNA	Q5ZYL1	YP_094405.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 401956 strand: 1 start: 400664	430	45891	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.	beta-ketoacyl-acyl-carrier-protein synthase II activity	fatty acid biosynthetic process	accession: cd00834 name: KAS_I_II desc: Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS)					MKRRVAITGL...
lpg0362	Q5ZYL0_LEGPH	3-oxoacyl-(Acyl carrier protein) synthase II, N-terminal	fabF	2.3.1.41	Q5ZYL0	unreviewed	mRNA	Q5ZYL0	YP_094406.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 403234 strand: 1 start: 401957	425	46094		3-oxoacyl-[acyl-carrier-protein] synthase activity	metabolic process	accession: cl09938 name: cond_enzymes super family desc: Condensing enzymes accession: COG0304 name: FabB desc: 3-oxoacyl-(acyl-carrier-protein) synthase					MSQANRVFIT...
lpg0363	Q5ZYK9_LEGPH	Lipid A biosynthesis acyltransferase	waaM	2.3.1.-	Q5ZYK9	unreviewed	mRNA	Q5ZYK9	YP_094407.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 404072 strand: 1 start: 403227	281	32731		transferase activity, transferring acyl groups		accession: cd07984 name: LPLAT_LABLAT-like desc: Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like	integral component of membrane				MNNLAQQIEA...
lpg0364	Q5ZYK8_LEGPH	Uncharacterized protein			Q5ZYK8	unreviewed	mRNA	Q5ZYK8	YP_094408.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 404487 strand: -1 start: 404182	101	11899		cyclic-di-GMP binding		accession: pfam07238 name: PilZ desc: PilZ domain			method: X-ray chains: A=1-101 id: 4Q63		MDERRKYFRL...
lpg0365	Q5ZYK7_LEGPH	Uncharacterized protein			Q5ZYK7	unreviewed	mRNA	Q5ZYK7	YP_094409.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 407352 strand: -1 start: 404662	896	103011									MVDFDKPVSK...
lpg0366	DAPF_LEGPH	Diaminopimelate epimerase	dapF	5.1.1.7	Q5ZYK6	reviewed	mRNA	Q5ZYK6	YP_094410.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 408496 strand: -1 start: 407663	277	29953	Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.	diaminopimelate epimerase activity	lysine biosynthetic process via diaminopimelate	accession: pfam01678 name: DAP_epimerase desc: Diaminopimelate epimerase accession: pfam01678 name: DAP_epimerase desc: Diaminopimelate epimerase accession: PRK00450 name: dapF desc: diaminopimelate epimerase	cytoplasm				MGIKFTKMHG...
lpg0367	Q5ZYK5_LEGPH	Uncharacterized protein			Q5ZYK5	unreviewed	mRNA	Q5ZYK5	YP_094411.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 409034 strand: -1 start: 408711	107	12795									MVPIQTGYME...
lpg0368	Q5ZYK4_LEGPH	Uncharacterized protein			Q5ZYK4	unreviewed	mRNA	Q5ZYK4	YP_094412.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 409140 strand: 1 start: 409033	35	3767					integral component of membrane				MQISSGGIKA...
lpg0369	Q5ZYK3_LEGPH	Carboxylesterase/phospholipase			Q5ZYK3	unreviewed	mRNA	Q5ZYK3	YP_094413.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 409992 strand: 1 start: 409315	225	25331		hydrolase activity		accession: cl21494 name: Abhydrolase super family desc: alpha/beta hydrolase					MRGEFVLSVY...
lpg0370	Q5ZYK2_LEGPH	Oligoketide cyclase/lipid transporter protein			Q5ZYK2	unreviewed	mRNA	Q5ZYK2	YP_094414.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 410423 strand: 1 start: 409989	144	16640				accession: cd07813 name: COQ10p_like desc: Coenzyme Q-binding protein COQ10p and similar proteins					MTIVKRSRTV...
lpg0371	Q5ZYK1_LEGPH	UPF0125 protein lpg0371			Q5ZYK1	unreviewed	mRNA	Q5ZYK1	YP_094415.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 410682 strand: 1 start: 410410	90	10425				accession: pfam03658 name: Ub-RnfH desc: RnfH family Ubiquitin					MVKVELVYIA...
lpg0372	Q5ZYK0_LEGPH	Small protein A, tmRNA-binding	smpA		Q5ZYK0	unreviewed	mRNA	Q5ZYK0	YP_094416.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 411115 strand: -1 start: 410771	114	13256				accession: pfam04355 name: SmpA_OmlA desc: SmpA / OmlA family	outer membrane				MAKFFMVGKK...
lpg0373	Q5ZYJ9_LEGPH	Components of sensory transduction system			Q5ZYJ9	unreviewed	mRNA	Q5ZYJ9	YP_094417.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 413186 strand: 1 start: 412548	212	24171				accession: cd01949 name: GGDEF desc: Diguanylate-cyclase (DGC) or GGDEF domain	integral component of membrane				MPMNFPIIAY...
lpg0374	Q5ZYJ8_LEGPH	Uncharacterized protein			Q5ZYJ8	unreviewed	mRNA	Q5ZYJ8	YP_094418.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 413885 strand: -1 start: 413499	128	14215									MKKWTVLAAS...
lpg0375	Q5ZYJ7_LEGPH	Uncharacterized protein			Q5ZYJ7	unreviewed	mRNA	Q5ZYJ7	YP_094419.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 414740 strand: 1 start: 414141	199	22645									MYSSLFLKKD...
lpg0376	Q5ZYJ6_LEGPH	SdhA, GRIP coiled-coil protein GCC185	sdhA		Q5ZYJ6	unreviewed	mRNA	Q5ZYJ6	YP_094420.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 419069 strand: -1 start: 414780	1429	166340									MISEKIKLLE...
lpg0377	Q5ZYJ5_LEGPH	Uncharacterized protein			Q5ZYJ5	unreviewed	mRNA	Q5ZYJ5	YP_094421.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 419975 strand: -1 start: 419232	247	28729		N-acetylmuramoyl-L-alanine amidase activity	peptidoglycan catabolic process	accession: cl01522 name: FGase super family desc: N-formylglutamate amidohydrolase					MNNLPPDIMK...
lpg0378	Q5ZYJ4_LEGPH	AF2307			Q5ZYJ4	unreviewed	mRNA	Q5ZYJ4	YP_094422.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 421212 strand: -1 start: 419956	418	47971		glutamate-cysteine ligase activity	cellular modified amino acid biosynthetic process	accession: cl00954 name: GCS2 super family desc: Glutamate-cysteine ligase family 2(GCS2)					MSSYNEFAGN...
lpg0379	Q5ZYJ3_LEGPH	Ribosomal protein S6 modification protein			Q5ZYJ3	unreviewed	mRNA	Q5ZYJ3	YP_094423.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 422623 strand: -1 start: 421169	484	55944		ATP binding metal ion binding		accession: pfam14401 name: RLAN desc: RimK-like ATPgrasp N-terminal domain accession: cl17255 name: ATP-grasp_4 super family desc: ATP-grasp domain accession: COG0189 name: RimK desc: Glutathione synthase/RimK-type ligase					MQTVIVTDDL...
lpg0380	Q5ZYJ2_LEGPH	Uncharacterized protein			Q5ZYJ2	unreviewed	mRNA	Q5ZYJ2	YP_094424.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 423346 strand: -1 start: 422627	239	27152				accession: cl00296 name: Peptidase_C39_like super family desc: Peptidase family C39					MPMIDLIIQT...
lpg0381	Q5ZYJ1_LEGPH	Uncharacterized protein			Q5ZYJ1	unreviewed	mRNA	Q5ZYJ1	YP_094425.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 424008 strand: -1 start: 423535	157	18119				accession: cl00509 name: hot_dog super family desc: The hotdog fold was initially identified in the E. coli FabA					MSPLTQFKFF...
lpg0382	Q5ZYJ0_LEGPH	Osmotically inducible protein Y	osmY		Q5ZYJ0	unreviewed	mRNA	Q5ZYJ0	YP_094426.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 424571 strand: -1 start: 424005	188	20435				accession: pfam04972 name: BON desc: BON domain This domain is found in a family of osmotic shock protection proteins accession: pfam04972 name: BON desc: BON domain This domain is found in a family of osmotic shock protection proteins					MEDTTMPKCM...
lpg0383	Q5ZYI9_LEGPH	Uncharacterized protein			Q5ZYI9	unreviewed	mRNA	Q5ZYI9	YP_094427.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 425297 strand: -1 start: 424815	160	17813				accession: cl12928 name: IcmL super family desc: Macrophage killing protein with similarity to conjugation protein					MMRNRDFNMK...
lpg0384	Q5ZYI8_LEGPH	UvrABC system protein A	uvrA		Q5ZYI8	unreviewed	mRNA	Q5ZYI8	YP_094428.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 428224 strand: 1 start: 425369	951	105494	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.	ATP binding ATPase activity DNA binding excinuclease ABC activity zinc ion binding	nucleotide-excision repair SOS response	accession: cd03271 name: ABC_UvrA_II desc: ATP-binding cassette domain II of the excision repair protein UvrA accession: cd03270 name: ABC_UvrA_I desc: ATP-binding cassette domain I of the excision repair protein UvrA accession: cd03270 name: ABC_UvrA_I desc: ATP-binding cassette domain I of the excision repair protein UvrA accession: PRK00349 name: uvrA desc: excinuclease ABC subunit A	cytoplasm excinuclease repair complex				MHTITIRGAR...
lpg0385	Q5ZYI7_LEGPH	LemA protein			Q5ZYI7	unreviewed	mRNA	Q5ZYI7	YP_094429.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 428988 strand: 1 start: 428407	193	22094				accession: pfam04011 name: LemA desc: LemA family The members of this family are related to the LemA protein					MKTFFIAILI...
lpg0386	Q5ZYI6_LEGPH	Heat shock protein HtpX	htpX	3.4.24.-	Q5ZYI6	unreviewed	mRNA	Q5ZYI6	YP_094430.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 430018 strand: 1 start: 428999	339	38870		metalloendopeptidase activity		accession: cl12018 name: Peptidase_M48 super family desc: Peptidase family M48 accession: PRK02870 name: PRK02870 desc: heat shock protein HtpX Provisional	integral component of membrane	Zn(2+)			MGIADYHATA...
lpg0387	Q5ZYI5_LEGPH	Transport permease protein			Q5ZYI5	unreviewed	mRNA	Q5ZYI5	YP_094431.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 430818 strand: -1 start: 430045	257	28800			transport	accession: PRK15066 name: PRK15066 desc: inner membrane transport permease Provisional accession: COG0842 name: YadH desc: ABC-type multidrug transport system, permease component [Defense mechanisms]	integral component of membrane plasma membrane				MGFKYQLIAL...
lpg0388	Q5ZYI4_LEGPH	ABC transporter, ATP binding component			Q5ZYI4	unreviewed	mRNA	Q5ZYI4	YP_094432.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 431722 strand: -1 start: 430808	304	34211		ATP binding ATPase activity		accession: cl21455 name: P-loop_NTPase super family desc: P-loop containing Nucleoside Triphosphate Hydrolases accession: COG1131 name: CcmA desc: ABC-type multidrug transport system, ATPase component [Defense mechanisms]					MHALEIKQLS...
lpg0389	Q5ZYI3_LEGPH	Uncharacterized protein			Q5ZYI3	unreviewed	mRNA	Q5ZYI3	YP_094433.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 431895 strand: 1 start: 431782	37	4315									MDFNSSLTSN...
lpg0390	Q5ZYI2_LEGPH	VipA	vipA		Q5ZYI2	unreviewed	mRNA	Q5ZYI2	YP_094434.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 433011 strand: -1 start: 431953	352	39622				accession: pfam11932 name: DUF3450 desc: Protein of unknown function (DUF3450)					MKHYDSMDQE...
lpg0391	Q5ZYI1_LEGPH	SM20-related protein			Q5ZYI1	unreviewed	mRNA	Q5ZYI1	YP_094435.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 433637 strand: -1 start: 433098	179	21050		iron ion binding L-ascorbic acid binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen		accession: cl21496 name: 2OG-FeII_Oxy super family desc: 2OG-Fe(II) oxygenase superfamily					MAYELKQQNL...
lpg0392	Q5ZYI0_LEGPH	Zinc metalloprotease			Q5ZYI0	unreviewed	mRNA	Q5ZYI0	YP_094436.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 434529 strand: -1 start: 433822	235	28030		metallopeptidase activity		accession: pfam01863 name: DUF45 desc: Protein of unknown function DUF45					MHIQIDGIPI...
lpg0393	Q5ZYH9_LEGPH	Uncharacterized protein			Q5ZYH9	unreviewed	mRNA	Q5ZYH9	YP_094437.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 436007 strand: 1 start: 435144	287	33421							method: X-ray chains: A/B/C/D=1-287 id: 4R0G		MLSSTKEYLQ...
lpg0394	Q5ZYH8_LEGPH	Methylated DNA protein cysteine S-methyltransferase		2.1.1.63	Q5ZYH8	unreviewed	mRNA	Q5ZYH8	YP_094438.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 436563 strand: -1 start: 436108	151	16673		methylated-DNA-[protein]-cysteine S-methyltransferase activity	DNA repair	accession: pfam01035 name: DNA_binding_1 desc: 6-O-methylguanine DNA methyltransferase, DNA binding domain accession: COG0350 name: AdaB desc: O6-methylguanine-DNA--protein-cysteine methyltransferase					MLLMSIFNTP...
lpg0395	RL19_LEGPH	50S ribosomal protein L19	rplS		Q5ZYH7	reviewed	mRNA	Q5ZYH7	YP_094439.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 436944 strand: -1 start: 436579	121	13668	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	structural constituent of ribosome	translation	accession: PRK05338 name: rplS desc: 50S ribosomal protein L19 Provisional	ribosome				MTNIIDQINA...
lpg0396	TRMD_LEGPH	tRNA (guanine-N(1)-)-methyltransferase	trmD	2.1.1.228	Q5ZYH6	reviewed	mRNA	Q5ZYH6	YP_094440.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 437741 strand: -1 start: 436971	250	28022	Specifically methylates guanosine-37 in various tRNAs.	tRNA (guanine(37)-N(1))-methyltransferase activity		accession: PRK00026 name: trmD desc: tRNA (guanine-N(1)-)-methyltransferase	cytoplasm				MALHLGVITL...
lpg0397	RIMM_LEGPH	Ribosome maturation factor RimM	rimM		Q5ZYH5	reviewed	mRNA	Q5ZYH5	YP_094441.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 438232 strand: -1 start: 437723	169	19229	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.	ribosome binding	ribosomal small subunit biogenesis rRNA processing	accession: pfam01782 name: RimM desc: RimM N-terminal domain accession: pfam05239 name: PRC desc: PRC-barrel domain accession: PRK00122 name: rimM desc: 16S rRNA-processing protein RimM Provisional	ribosome				MNNKTNWVII...
lpg0398	Q5ZYH4_LEGPH	Uncharacterized protein			Q5ZYH4	unreviewed	mRNA	Q5ZYH4	YP_094442.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 438241 strand: 1 start: 438107	44	4855									MPVIVPQDII...
lpg0399	RS16_LEGPH	30S ribosomal protein S16	rpsP		Q5ZYH3	reviewed	mRNA	Q5ZYH3	YP_094443.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 438498 strand: -1 start: 438238	86	9940		structural constituent of ribosome	translation	accession: PRK00040 name: rpsP desc: 30S ribosomal protein S16	ribosome				MVVIRLSRAG...
lpg0400	Q5ZYH2_LEGPH	Signal recognition particle protein	ffh		Q5ZYH2	unreviewed	mRNA	Q5ZYH2	YP_094444.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 439961 strand: -1 start: 438585	458	50827	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	7S RNA binding GTP binding GTPase activity	SRP-dependent cotranslational protein targeting to membrane	accession: smart00962 name: SRP54 desc: SRP54-type protein, GTPase domain accession: pfam02978 name: SRP_SPB desc: Signal peptide binding domain accession: pfam02881 name: SRP54_N desc: SRP54-type protein, helical bundle domain accession: PRK10867 name: PRK10867 desc: signal recognition particle protein Provisional	signal recognition particle				MFDNLTERLT...
lpg0401	Q5ZYH1_LEGPH	Uncharacterized protein			Q5ZYH1	unreviewed	mRNA	Q5ZYH1	YP_094445.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 440887 strand: -1 start: 440213	224	25657									MESLMPKAFT...
lpg0402	Q5ZYH0_LEGPH	Putative ankyrin-repeat containing protein	legA9		Q5ZYH0	unreviewed	mRNA	Q5ZYH0	YP_094446.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 443024 strand: 1 start: 441321	567	62129				accession: cd00204 name: ANK desc: ankyrin repeats accession: pfam12796 name: Ank_2 desc: Ankyrin repeats (3 copies)					MHSLYLGVVK...
lpg0403	Q5ZYG9_LEGPH	Ankyrin repeat-containing protein	legA7		Q5ZYG9	unreviewed	mRNA	Q5ZYG9	YP_094447.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 444748 strand: 1 start: 443204	514	58705				accession: cd00204 name: ANK desc: ankyrin repeats accession: pfam12796 name: Ank_2 desc: Ankyrin repeats (3 copies) accession: pfam12796 name: Ank_2 desc: Ankyrin repeats (3 copies)	integral component of membrane				MNSLWIASGS...
lpg0404	Q5ZYG8_LEGPH	Amino acid antiporter			Q5ZYG8	unreviewed	mRNA	Q5ZYG8	YP_094448.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 446488 strand: 1 start: 445085	467	50463		amino acid transmembrane transporter activity		accession: TIGR03813 name: put_Glu_GABA_T desc: putative glutamate/gamma-aminobutyrate antiporter	integral component of membrane				MSNKKHSLTI...
lpg0405	Q5ZYG7_LEGPH	Uncharacterized protein			Q5ZYG7	unreviewed	mRNA	Q5ZYG7	YP_094449.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 447068 strand: 1 start: 446478	196	22515									MLYNLTRQVK...
lpg0406	Q5ZYG6_LEGPH	Alkyl hydroperoxide reductase AhpD		1.11.1.15	Q5ZYG6	unreviewed	mRNA	Q5ZYG6	YP_094450.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 447609 strand: 1 start: 447268	113	12295	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.	peroxidase activity peroxiredoxin activity		accession: COG0599 name: YurZ desc: Uncharacterized conserved protein YurZ			method: X-ray chains: A/B/C=1-113 id: 5DIK method: X-ray chains: A/B=1-113 id: 5DIP		MSDKFSHITK...
lpg0407	Q5ZYG5_LEGPH	Uncharacterized protein			Q5ZYG5	unreviewed	mRNA	Q5ZYG5	YP_094451.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 448265 strand: -1 start: 447822	147	16350									MRLLFISLIL...
lpg0408	Q5ZYG4_LEGPH	Inner (Transmembrane) protein			Q5ZYG4	unreviewed	mRNA	Q5ZYG4	YP_094452.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 448832 strand: -1 start: 448284	182	20485		protein disulfide oxidoreductase activity		accession: cl00649 name: DsbB super family desc: Disulfide bond formation protein DsbB	integral component of membrane plasma membrane				MNKQMQWHLF...
lpg0409	Q5ZYG3_LEGPH	SURF1-like protein			Q5ZYG3	unreviewed	mRNA	Q5ZYG3	YP_094453.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 450248 strand: 1 start: 449520	242	28490				accession: cd06662 name: SURF1 desc: SURF1 superfamily.	integral component of membrane plasma membrane				MPSLTCFNFR...
lpg0410	Q5ZYG2_LEGPH	Uncharacterized protein			Q5ZYG2	unreviewed	mRNA	Q5ZYG2	YP_094454.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 450777 strand: 1 start: 450232	181	20533									MKKPYKYMTL...
lpg0411	Q5ZYG1_LEGPH	Cytochrome c oxidase assembly protein			Q5ZYG1	unreviewed	mRNA	Q5ZYG1	YP_094455.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 451789 strand: 1 start: 450758	343	37975		oxidoreductase activity, acting on the CH-CH group of donors	heme a biosynthetic process	accession: pfam02628 name: COX15-CtaA desc: Cytochrome oxidase assembly protein	integral component of membrane				MKLRADKLMS...
lpg0412	CYOE_LEGPH	Protoheme IX farnesyltransferase		2.5.1.-	Q5ZYG0	reviewed	mRNA	Q5ZYG0	YP_094456.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 452663 strand: 1 start: 451779	294	33058	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.	protoheme IX farnesyltransferase activity	heme O biosynthetic process	accession: PRK04375 name: PRK04375 desc: protoheme IX farnesyltransferase Provisional	integral component of membrane plasma membrane				MRTEYAARLP...
lpg0413	Q5ZYF9_LEGPH	Hypothetical, SCO1/SenC family protein			Q5ZYF9	unreviewed	mRNA	Q5ZYF9	YP_094457.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 453314 strand: 1 start: 452673	213	23788			cell redox homeostasis	accession: cd02968 name: SCO desc: SCO (an acronym for Synthesis of Cytochrome c Oxidase) family	cell				MNIKIKGGAV...
lpg0414	RIMK_LEGPH	Probable alpha-L-glutamate ligase		6.3.2.-	Q5ZYF8	reviewed	mRNA	Q5ZYF8	YP_094458.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 454589 strand: 1 start: 453681	302	32881		acid-amino acid ligase activity ATP binding magnesium ion binding manganese ion binding	cellular protein modification process translation	accession: cl17255 name: ATP-grasp_4 super family desc: ATP-grasp domain		Mg(2+)			MKIAILATNP...
lpg0415	Q5ZYF7_LEGPH	Uncharacterized protein			Q5ZYF7	unreviewed	mRNA	Q5ZYF7	YP_094459.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 454838 strand: -1 start: 454593	81	8958		DNA binding		accession: PRK13355 name: PRK13355 desc: bifunctional HTH-domain containing protein/aminotransferase Provisional					MLNKRFSERL...
lpg0416	Q5ZYF6_LEGPH	Glucose-6-phosphate 1-dehydrogenase	zwf	1.1.1.49	Q5ZYF6	unreviewed	mRNA	Q5ZYF6	YP_094460.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 456646 strand: 1 start: 455156	496	57296	Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.	glucose-6-phosphate dehydrogenase activity NADP binding	glucose metabolic process pentose-phosphate shunt	accession: pfam02781 name: G6PD_C desc: Glucose-6-phosphate dehydrogenase, C-terminal domain accession: pfam00479 name: G6PD_N desc: Glucose-6-phosphate dehydrogenase, NAD binding domain accession: PRK05722 name: PRK05722 desc: glucose-6-phosphate 1-dehydrogenase					MLLKAESKYP...
lpg0417	Q5ZYF5_LEGPH	6-phosphogluconolactonase	pgl	3.1.1.31	Q5ZYF5	unreviewed	mRNA	Q5ZYF5	YP_094461.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 457346 strand: 1 start: 456615	243	27311		6-phosphogluconolactonase activity	carbohydrate metabolic process pentose-phosphate shunt	accession: cd01400 name: 6PGL desc: 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily					MFGVITMQFH...
lpg0418	Q5ZYF4_LEGPH	6-phosphogluconate dehydratase	edd	4.2.1.12	Q5ZYF4	unreviewed	mRNA	Q5ZYF4	YP_094462.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 459172 strand: 1 start: 457334	612	65268		phosphogluconate dehydratase activity	Entner-Doudoroff pathway through 6-phosphogluconate	accession: PRK09054 name: PRK09054 desc: phosphogluconate dehydratase					MHPVINQVTE...
lpg0419	Q5ZYF3_LEGPH	Glucokinase	glk	2.7.1.2	Q5ZYF3	unreviewed	mRNA	Q5ZYF3	YP_094463.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 460154 strand: 1 start: 459147	335	36835		ATP binding glucokinase activity	glycolytic process	accession: pfam02685 name: Glucokinase desc: Glucokinase	cytoplasm				MNFFMMPHDL...
lpg0420	Q5ZYF2_LEGPH	Multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase/(4-hydroxy-2-oxoglutarate aldolase)	eda		Q5ZYF2	unreviewed	mRNA	Q5ZYF2	YP_094464.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 460803 strand: 1 start: 460141	220	23389		lyase activity	metabolic process	accession: PRK05718 name: PRK05718 desc: keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase Provisional					MSFSEWKTQP...
lpg0421	Q5ZYF1_LEGPH	D-xylose (Galactose, arabinose)-proton symporter	ywtG		Q5ZYF1	unreviewed	mRNA	Q5ZYF1	YP_094465.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 462337 strand: 1 start: 460916	473	51320		substrate-specific transmembrane transporter activity		accession: cd06174 name: MFS desc: The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters ... accession: pfam00083 name: Sugar_tr desc: Sugar (and other) transporter	integral component of membrane				MAWIVAIIGS...
lpg0422	Q5ZYF0_LEGPH	Glucoamylase	legY	3.2.1.3	Q5ZYF0	unreviewed	mRNA	Q5ZYF0	YP_094466.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 463776 strand: -1 start: 462427	449	51979		glucan 1,4-alpha-glucosidase activity	polysaccharide metabolic process	accession: cl08284 name: Glyco_hydro_15 super family desc: Glycosyl hydrolases family 15					MATFFFKTNY...
lpg0423	Q5ZYE9_LEGPH	Transcriptional regulator, cro family	yozG		Q5ZYE9	unreviewed	mRNA	Q5ZYE9	YP_094467.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 464138 strand: -1 start: 463902	78	8743		sequence-specific DNA binding		accession: COG3655 name: YozG desc: DNA-binding transcriptional regulator, XRE family [Transcription]					MSIIVNLDVM...
lpg0424	Q5ZYE8_LEGPH	Uncharacterized protein			Q5ZYE8	unreviewed	mRNA	Q5ZYE8	YP_094468.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 464764 strand: -1 start: 464225	179	20374				accession: pfam11188 name: DUF2975 desc: Protein of unknown function (DUF2975)	integral component of membrane				MKKIKSVSHL...
lpg0425	HEMH_LEGPH	Ferrochelatase	hemH	4.99.1.1	Q5ZYE7	reviewed	mRNA	Q5ZYE7	YP_094469.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 465890 strand: -1 start: 464892	331	37804	Catalyzes the ferrous insertion into protoporphyrin IX.	ferrochelatase activity metal ion binding	heme biosynthetic process	accession: cd00419 name: Ferrochelatase_C desc: Ferrochelatase, C-terminal domain accession: cd03411 name: Ferrochelatase_N desc: Ferrochelatase, N-terminal domain accession: PRK00035 name: hemH desc: ferrochelatase	cytoplasm				MRRGLLLLNL...
lpg0426	Q5ZYE6_LEGPH	Cold shock protein CspD	cspD		Q5ZYE6	unreviewed	mRNA	Q5ZYE6	YP_094470.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 466231 strand: -1 start: 465998	77	8304		DNA binding	regulation of transcription, DNA-templated transcription, DNA-templated	accession: COG1278 name: CspC desc: Cold shock protein, CspA family [Transcription]	cytoplasm				MARGEVKWFN...
lpg0427	Q5ZYE5_LEGPH	Diadenosine tetraphosphate (Ap4A) hydrolase, histidine triad family protein			Q5ZYE5	unreviewed	mRNA	Q5ZYE5	YP_094471.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 466899 strand: 1 start: 466588	103	11690		hydrolase activity		accession: cl00228 name: HIT_like super family desc: HIT family: HIT (Histidine triad) proteins					MDIQEIHQLE...
lpg0428	Q5ZYE4_LEGPH	Uncharacterized protein			Q5ZYE4	unreviewed	mRNA	Q5ZYE4	YP_094472.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 467541 strand: -1 start: 467113	142	15594				accession: cd06587 name: Glo_EDI_BRP_like desc: This domain superfamily is found in a variety of structurally related metalloproteins					MFIIVIYNSS...
lpg0429	Q5ZYE3_LEGPH	Outer membrane efflux protein	oprM		Q5ZYE3	unreviewed	mRNA	Q5ZYE3	YP_094473.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 468911 strand: 1 start: 467559	450	50872		transporter activity		accession: pfam02321 name: OEP desc: Outer membrane efflux protein accession: pfam02321 name: OEP desc: Outer membrane efflux protein					MMCMLKKLMF...
lpg0430	Q5ZYE2_LEGPH	Multidrug resistance efflux pump PmrA			Q5ZYE2	unreviewed	mRNA	Q5ZYE2	YP_094474.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 470088 strand: 1 start: 469036	350	40219				accession: pfam13533 name: Biotin_lipoyl_2 desc: Biotin-lipoyl like accession: pfam13437 name: HlyD_3 desc: HlyD family secretion protein accession: cl24690 name: PMT_4TMC super family desc: C-terminal four TMM region of protein-O-mannosyltransferase accession: COG1566 name: EmrA desc: Multidrug resistance efflux pump [Defense mechanisms]	integral component of membrane				MVGYFMKKLM...
lpg0431	Q5ZYE1_LEGPH	Uncharacterized protein			Q5ZYE1	unreviewed	mRNA	Q5ZYE1	YP_094475.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 470998 strand: 1 start: 470060	312	36750				accession: cl00857 name: DUF63 super family desc: Membrane protein of unknown function DUF63 accession: cl07347 name: GET2 super family desc: GET complex subunit GET2	integral component of membrane				MLMSMSKFIE...
lpg0432	Q5ZYE0_LEGPH	Uncharacterized protein			Q5ZYE0	unreviewed	mRNA	Q5ZYE0	YP_094476.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 471864 strand: 1 start: 470965	299	35025				accession: pfam13515 name: FUSC_2 desc: Fusaric acid resistance protein-like	integral component of membrane				MESIMHDTSA...
lpg0433	Q5ZYD9_LEGPH	Uncharacterized protein			Q5ZYD9	unreviewed	mRNA	Q5ZYD9	YP_094477.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 472266 strand: 1 start: 471886	126	14578				accession: COG1733 name: HxlR desc: DNA-binding transcriptional regulator, HxlR family [Transcription]					MSHPHYSVYN...
lpg0434	Q5ZYD8_LEGPH	Uncharacterized protein			Q5ZYD8	unreviewed	mRNA	Q5ZYD8	YP_094478.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 472795 strand: -1 start: 472268	175	21042				accession: cl18775 name: COG4278 super family desc: Uncharacterized protein [Function unknown]					MAQELVLDDI...
lpg0435	Q5ZYD7_LEGPH	SAM-dependent methyltransferase			Q5ZYD7	unreviewed	mRNA	Q5ZYD7	YP_094479.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 473572 strand: 1 start: 472961	203	23322		methyltransferase activity		accession: pfam12847 name: Methyltransf_18 desc: Methyltransferase domain accession: COG0500 name: SmtA desc: SAM-dependent methyltransferase					MNKRNWTAYY...
lpg0436	Q5ZYD6_LEGPH	Ankyrin repeat-containing protein	legA11		Q5ZYD6	unreviewed	mRNA	Q5ZYD6	YP_094480.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 474548 strand: -1 start: 473739	269	30652				accession: cd00204 name: ANK desc: ankyrin repeats accession: pfam12796 name: Ank_2 desc: Ankyrin repeats (3 copies)			method: X-ray chains: A=1-114 id: 4ZHB		MIKMGRSEMK...
lpg0437	Q5ZYD5_LEGPH	Uncharacterized protein			Q5ZYD5	unreviewed	mRNA	Q5ZYD5	YP_094481.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 476811 strand: 1 start: 474811	666	75874									MQNLDEILKK...
lpg0438	Q5ZYD4_LEGPH	Uncharacterized protein			Q5ZYD4	unreviewed	mRNA	Q5ZYD4	YP_094482.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 477314 strand: -1 start: 477096	72	8620									MQIFYLFEFN...
lpg0439	Q5ZYD3_LEGPH	Uncharacterized protein			Q5ZYD3	unreviewed	mRNA	Q5ZYD3	YP_094483.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 478539 strand: -1 start: 477490	349	39482					integral component of membrane		method: X-ray chains: A/B=94-308 id: 5L0L		MADHSPFIKF...
lpg0440	Q5ZYD2_LEGPH	Uncharacterized protein			Q5ZYD2	unreviewed	mRNA	Q5ZYD2	YP_094484.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 478843 strand: 1 start: 478631	70	7810									MDIHSTYKML...
lpg0441	Q5ZYD1_LEGPH	IcmT	icmT		Q5ZYD1	unreviewed	mRNA	Q5ZYD1	YP_094485.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 479274 strand: 1 start: 479014	86	9921					integral component of membrane				MAGGFSATSH...
lpg0442	Q5ZYD0_LEGPH	IcmS	icmS		Q5ZYD0	unreviewed	mRNA	Q5ZYD0	YP_094486.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 479619 strand: 1 start: 479275	114	12673				accession: pfam12608 name: T4bSS_IcmS desc: Type IVb secretion, IcmS, effector-recruitment					MERDISKCMA...
lpg0443	Q5ZYC9_LEGPH	IcmR	icmR		Q5ZYC9	unreviewed	mRNA	Q5ZYC9	YP_094487.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 480081 strand: 1 start: 479719	120	12947							method: X-ray chains: B/D=23-95 id: 3FXD method: X-ray chains: B=23-95 id: 3FXE method: X-ray chains: R=1-120 id: 4EYY		MGNNTDDSAR...
lpg0444	Q5ZYC8_LEGPH	IcmQ	icmQ		Q5ZYC8	unreviewed	mRNA	Q5ZYC8	YP_094488.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 480747 strand: 1 start: 480148	199	22409				accession: pfam09475 name: Dot_icm_IcmQ desc: Dot/Icm secretion system protein (dot_icm_IcmQ)					MVPISIEVMK...
lpg0445	Q5ZYC7_LEGPH	IcmP (DotM)	icmP		Q5ZYC7	unreviewed	mRNA	Q5ZYC7	YP_094489.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 482064 strand: 1 start: 480922	380	43814					integral component of membrane				MYIEMAQQQQ...
lpg0446	Q5ZYC6_LEGPH	IcmO (DotL)	icmO		Q5ZYC6	unreviewed	mRNA	Q5ZYC6	YP_094490.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 484412 strand: 1 start: 482061	783	87503				accession: cl21455 name: P-loop_NTPase super family desc: P-loop containing Nucleoside Triphosphate Hydrolases	integral component of membrane				MMRGIDSRHE...
lpg0447	Q5ZYC5_LEGPH	LphA (DotK)	lphA		Q5ZYC5	unreviewed	mRNA	Q5ZYC5	YP_094491.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 485385 strand: 1 start: 484816	189	21071				accession: cd07185 name: OmpA_C-like desc: Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA					MRSLRTNYIY...
lpg0448	Q5ZYC4_LEGPH	IcmM (DotJ)	icmM		Q5ZYC4	unreviewed	mRNA	Q5ZYC4	YP_094492.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 485681 strand: 1 start: 485397	94	10679					integral component of membrane				MSRETWALIK...
lpg0449	Q5ZYC3_LEGPH	IcmL (DotI)	icmL		Q5ZYC3	unreviewed	mRNA	Q5ZYC3	YP_094493.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 486335 strand: 1 start: 485697	212	23125				accession: pfam11393 name: IcmL desc: Macrophage killing protein with similarity to conjugation protein	integral component of membrane				MAEDALTVVA...
lpg0450	Q5ZYC2_LEGPH	IcmK (DotH)	icmK		Q5ZYC2	unreviewed	mRNA	Q5ZYC2	YP_094494.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 487420 strand: 1 start: 486335	361	38926				accession: pfam12293 name: T4BSS_DotH_IcmK desc: Putative outer membrane core complex of type IVb secretion					MMKKYDQLCK...
lpg0451	Q5ZYC1_LEGPH	IcmE (DotG)	icmE		Q5ZYC1	unreviewed	mRNA	Q5ZYC1	YP_094495.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 490571 strand: 1 start: 487425	1048	107807				accession: pfam03743 name: TrbI desc: Bacterial conjugation TrbI-like protein accession: pfam13599 name: Pentapeptide_4 desc: Pentapeptide repeats (9 copies)	integral component of membrane				MASKKENLKS...
lpg0452	Q5ZYC0_LEGPH	IcmG (DotF)	icmG		Q5ZYC0	unreviewed	mRNA	Q5ZYC0	YP_094496.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 491395 strand: 1 start: 490586	269	29701				accession: cl24006 name: YidC_periplas super family desc: YidC periplasmic domain	integral component of membrane				MMAEHDQNND...
lpg0453	Q5ZYB9_LEGPH	IcmC (DotE)	icmC		Q5ZYB9	unreviewed	mRNA	Q5ZYB9	YP_094497.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 491987 strand: 1 start: 491403	194	20276					integral component of membrane				MADPTCTGGT...
lpg0454	Q5ZYB8_LEGPH	IcmD (DotP)	icmD		Q5ZYB8	unreviewed	mRNA	Q5ZYB8	YP_094498.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 492411 strand: 1 start: 492130	93	9433					integral component of membrane				MASQITGSFT...
lpg0455	Q5ZYB7_LEGPH	IcmJ (DotN)	icmJ		Q5ZYB7	unreviewed	mRNA	Q5ZYB7	YP_094499.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 493235 strand: 1 start: 492591	214	24424				accession: smart00507 name: HNHc desc: HNH nucleases					MNVNQTMADN...
lpg0456	Q5ZYB6_LEGPH	IcmB (DotO)	icmB		Q5ZYB6	unreviewed	mRNA	Q5ZYB6	YP_094500.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 496300 strand: 1 start: 493271	1009	112136				accession: pfam12846 name: AAA_10 desc: AAA-like domain					MANWSESFFE...
lpg0457	Q5ZYB5_LEGPH	TphA (ProP)	tphA		Q5ZYB5	unreviewed	mRNA	Q5ZYB5	YP_094501.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 497702 strand: -1 start: 496446	418	46069		transporter activity	transmembrane transport	accession: cd06174 name: MFS desc: Major Facilitator Superfamily (MFS)	integral component of membrane				MKQNTKHSII...
lpg0458	Q5ZYB4_LEGPH	IcmF	icmF		Q5ZYB4	unreviewed	mRNA	Q5ZYB4	YP_094502.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 500626 strand: -1 start: 497705	973	110807				accession: pfam06744 name: IcmF_C desc: Type VI secretion protein IcmF C-terminal accession: pfam14331 name: ImcF-related_N desc: ImcF-related N-terminal domain accession: cl06018 name: IcmF-related super family desc: Intracellular multiplication and human macrophage-killing					MDNSLRALCD...
lpg0459	Q5ZYB3_LEGPH	IcmH (DotU)	icmH		Q5ZYB3	unreviewed	mRNA	Q5ZYB3	YP_094503.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 501411 strand: -1 start: 500626	261	29688				accession: TIGR03349 name: IV_VI_DotU desc: type IV / VI secretion system protein, DotU family	integral component of membrane				MTTEQYPSSL...
lpg0460	Q5ZYB2_LEGPH	Bifunctional purine biosynthesis protein PurH	purH	3.5.4.10	Q5ZYB2	unreviewed	mRNA	Q5ZYB2	YP_094504.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 503285 strand: -1 start: 501696	529	57947		IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity	'de novo' IMP biosynthetic process	accession: smart00798 name: AICARFT_IMPCHas desc: AICARFT/IMPCHase bienzyme accession: cd01421 name: IMPCH desc: Inosine monophosphate cyclohydrolase domain accession: PRK00881 name: purH desc: bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase					MAKKQIYSSF...
lpg0461	PRMA_LEGPH	Ribosomal protein L11 methyltransferase	prmA	2.1.1.-	Q5ZYB1	reviewed	mRNA	Q5ZYB1	YP_094505.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 504181 strand: -1 start: 503312	289	32117	Methylates ribosomal protein L11.	protein methyltransferase activity		accession: cl17173 name: AdoMet_MTases super family desc: S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I accession: PRK00517 name: prmA desc: ribosomal protein L11 methyltransferase	cytoplasm				MWFQLKIEHC...
lpg0462	Q5ZYB0_LEGPH	Acetyl CoA carboxylase, biotin carboxylase subunit	accC		Q5ZYB0	unreviewed	mRNA	Q5ZYB0	YP_094506.1	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	end: 505532 strand: -1 start: 504183	449	49244		ATP binding biotin carboxylase activity metal ion binding		accession: pfam02786 name: CPSase_L_D2 desc: Carbamoyl-phosphate synthase L chain, ATP binding domain accession: pfam00289 name: CPSase_L_chain desc: Carbamoyl-phosphate synthase L chain, N-terminal domain accession: smart00878 name: Biotin_carb_C desc: Biotin carboxylase C-terminal domain accession: PRK08591 name: PRK08591 desc: acetyl-CoA carboxylase biotin carboxylase subunit					MFMLSKIVIA...
lpg_3050	NaN	30S ribosomal protein S19				NaN	mRNA		YP_003856781.1		end: 385949 strand: 1 start: 385671	92					accession: PRK00357 name: rpsS desc: 30S ribosomal protein S19					MARSIRKGPF...

Índice | Anterior | Seguinte